1o2b

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1o2b]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O2B FirstGlance]. <br>
<table><tr><td colspan='2'>[[1o2b]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O2B FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1o24|1o24]], [[1o25|1o25]], [[1o26|1o26]], [[1o27|1o27]], [[1o28|1o28]], [[1o29|1o29]], [[1o2a|1o2a]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1o24|1o24]], [[1o25|1o25]], [[1o26|1o26]], [[1o27|1o27]], [[1o28|1o28]], [[1o29|1o29]], [[1o2a|1o2a]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TM0449 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 Thermotoga maritima])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TM0449 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 Thermotoga maritima])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o2b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1o2b RCSB], [http://www.ebi.ac.uk/pdbsum/1o2b PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o2b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1o2b RCSB], [http://www.ebi.ac.uk/pdbsum/1o2b PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/THYX_THEMA THYX_THEMA]] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Agarwalla, S.]]
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[[Category: Agarwalla, S]]
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[[Category: Canaves, J M.]]
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[[Category: Canaves, J M]]
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[[Category: Deacon, A M.]]
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[[Category: Deacon, A M]]
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[[Category: JCSG, Joint Center for Structural Genomics.]]
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[[Category: Kuhn, P.]]
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[[Category: Lesley, S A.]]
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[[Category: Mathews, I I.]]
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[[Category: McMullan, D.]]
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[[Category: Jcsg]]
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[[Category: Joint center for structural genomic]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
[[Category: Structural genomic]]
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[[Category: Kuhn, P]]
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[[Category: Lesley, S A]]
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[[Category: Mathews, I I]]
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[[Category: McMullan, D]]
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[[Category: Jcsg]]
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[[Category: PSI, Protein structure initiative]]
[[Category: Thymidylate synthase complementing protein]]
[[Category: Thymidylate synthase complementing protein]]
[[Category: Tm0449]]
[[Category: Tm0449]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 18:18, 24 December 2014

Crystal structure of Thymidylate Synthase Complementing Protein (TM0449) from Thermotoga maritima with FAD and PO4 at 2.45 A resolution

1o2b, resolution 2.45Å

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