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1jn1
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1jn1]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JN1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JN1 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1jn1]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JN1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JN1 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ISPF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 Haemophilus influenzae])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ISPF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 Haemophilus influenzae])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jn1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jn1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jn1 RCSB], [http://www.ebi.ac.uk/pdbsum/1jn1 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jn1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jn1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jn1 RCSB], [http://www.ebi.ac.uk/pdbsum/1jn1 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ISPF_HAEIN ISPF_HAEIN]] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).[HAMAP-Rule:MF_00107] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Haemophilus influenzae]] | [[Category: Haemophilus influenzae]] | ||
| - | [[Category: Eisenstein, E | + | [[Category: Eisenstein, E]] |
| - | [[Category: Herzberg, O | + | [[Category: Herzberg, O]] |
| - | [[Category: Howard, A | + | [[Category: Howard, A]] |
| - | [[Category: Krajewski, W | + | [[Category: Krajewski, W]] |
| - | [[Category: Lehmann, C | + | [[Category: Lehmann, C]] |
| - | [[Category: Lim, K | + | [[Category: Lim, K]] |
| - | [[Category: S2F, Structure 2.Function Project | + | [[Category: S2F, Structure 2.Function Project]] |
| - | [[Category: Toedt, J | + | [[Category: Toedt, J]] |
[[Category: 2c-methyl-d-erythritol 2]] | [[Category: 2c-methyl-d-erythritol 2]] | ||
[[Category: 4-cyclodiphosphate synthase]] | [[Category: 4-cyclodiphosphate synthase]] | ||
Revision as of 22:30, 25 December 2014
Structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Haemophilus influenzae (HI0671)
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Categories: Haemophilus influenzae | Eisenstein, E | Herzberg, O | Howard, A | Krajewski, W | Lehmann, C | Lim, K | S2F, Structure 2.Function Project | Toedt, J | 2c-methyl-d-erythritol 2 | 4-cyclodiphosphate synthase | Isoprenoid biosynthesis | Mecp | S2f | Structural genomic | Structure 2 function project | Unknown function
