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1l0i

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1l0i]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. The June 2007 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Fatty Acid Synthase'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2007_6 10.2210/rcsb_pdb/mom_2007_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L0I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L0I FirstGlance]. <br>
<table><tr><td colspan='2'>[[1l0i]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. The June 2007 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Fatty Acid Synthase'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2007_6 10.2210/rcsb_pdb/mom_2007_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L0I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L0I FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PSR:THIOBUTYRIC+ACID+S-{2-[3-(2-HYDROXY-3,3-DIMETHYL-4-PHOSPHONOOXY-BUTYRYLAMINO)-PROPIONYLAMINO]-ETHYL}+ESTER'>PSR</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PSR:THIOBUTYRIC+ACID+S-{2-[3-(2-HYDROXY-3,3-DIMETHYL-4-PHOSPHONOOXY-BUTYRYLAMINO)-PROPIONYLAMINO]-ETHYL}+ESTER'>PSR</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1l0h|1l0h]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1l0h|1l0h]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l0i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1l0i RCSB], [http://www.ebi.ac.uk/pdbsum/1l0i PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l0i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1l0i RCSB], [http://www.ebi.ac.uk/pdbsum/1l0i PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ACP_ECOLI ACP_ECOLI]] Carrier of the growing fatty acid chain in fatty acid biosynthesis.[HAMAP-Rule:MF_01217]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Fatty Acid Synthase]]
[[Category: Fatty Acid Synthase]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Baker, P J.]]
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[[Category: Baker, P J]]
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[[Category: Baldock, C.]]
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[[Category: Baldock, C]]
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[[Category: Gilroy, J.]]
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[[Category: Gilroy, J]]
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[[Category: Rafferty, J B.]]
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[[Category: Rafferty, J B]]
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[[Category: Rice, D W.]]
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[[Category: Rice, D W]]
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[[Category: Roujeinikova, A.]]
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[[Category: Roujeinikova, A]]
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[[Category: Simon, W J.]]
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[[Category: Simon, W J]]
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[[Category: Slabas, A R.]]
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[[Category: Slabas, A R]]
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[[Category: Stuitje, A R.]]
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[[Category: Stuitje, A R]]
[[Category: Acyl carrier protein]]
[[Category: Acyl carrier protein]]
[[Category: Acyl chain binding]]
[[Category: Acyl chain binding]]
[[Category: Fatty acid biosynthesis]]
[[Category: Fatty acid biosynthesis]]
[[Category: Lipid transport]]
[[Category: Lipid transport]]

Revision as of 20:11, 25 December 2014

Crystal structure of butyryl-ACP I62M mutant

1l0i, resolution 1.20Å

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