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1mut
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1mut]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MUT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MUT FirstGlance]. <br> | <table><tr><td colspan='2'>[[1mut]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MUT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MUT FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mut OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1mut RCSB], [http://www.ebi.ac.uk/pdbsum/1mut PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mut OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1mut RCSB], [http://www.ebi.ac.uk/pdbsum/1mut PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MUTT_ECOLI MUTT_ECOLI]] Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A.T to G.C transversions. MutT specifically degrades 8-oxo-dGTP to the monophosphate.<ref>PMID:1309939</ref> <ref>PMID:15850400</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Abeygunawardana, C | + | [[Category: Abeygunawardana, C]] |
| - | [[Category: Bessman, M J | + | [[Category: Bessman, M J]] |
| - | [[Category: Frick, D N | + | [[Category: Frick, D N]] |
| - | [[Category: Gittis, A G | + | [[Category: Gittis, A G]] |
| - | [[Category: Lin, J | + | [[Category: Lin, J]] |
| - | [[Category: Mildvan, A S | + | [[Category: Mildvan, A S]] |
| - | [[Category: Miller, A F | + | [[Category: Miller, A F]] |
| - | [[Category: Weber, D J | + | [[Category: Weber, D J]] |
[[Category: Dna repair]] | [[Category: Dna repair]] | ||
Revision as of 04:09, 25 December 2014
NMR STUDY OF MUTT ENZYME, A NUCLEOSIDE TRIPHOSPHATE PYROPHOSPHOHYDROLASE
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