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1m3v
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1m3v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M3V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M3V FirstGlance]. <br> | <table><tr><td colspan='2'>[[1m3v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M3V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M3V FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m3v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1m3v RCSB], [http://www.ebi.ac.uk/pdbsum/1m3v PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m3v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1m3v RCSB], [http://www.ebi.ac.uk/pdbsum/1m3v PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LDB1_MOUSE LDB1_MOUSE]] Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. May play a role in the development of motor neurons. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state.<ref>PMID:8918878</ref> <ref>PMID:8876198</ref> <ref>PMID:9192866</ref> <ref>PMID:9391090</ref> <ref>PMID:16815859</ref> <ref>PMID:9315627</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Deane, J E | + | [[Category: Deane, J E]] |
| - | [[Category: Kwan, A H.Y | + | [[Category: Kwan, A H.Y]] |
| - | [[Category: Mackay, J P | + | [[Category: Mackay, J P]] |
| - | [[Category: Matthews, J M | + | [[Category: Matthews, J M]] |
| - | [[Category: Sum, E Y | + | [[Category: Sum, E Y]] |
| - | [[Category: Visvader, J E | + | [[Category: Visvader, J E]] |
[[Category: Fusion protein]] | [[Category: Fusion protein]] | ||
[[Category: Ldb1]] | [[Category: Ldb1]] | ||
Revision as of 19:15, 24 December 2014
FLIN4: Fusion of the LIM binding domain of Ldb1 and the N-terminal LIM domain of LMO4
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