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1l7b
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1l7b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L7B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L7B FirstGlance]. <br> | <table><tr><td colspan='2'>[[1l7b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L7B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L7B FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DNLJ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DNLJ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_ligase_(NAD(+)) DNA ligase (NAD(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.2 6.5.1.2] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_ligase_(NAD(+)) DNA ligase (NAD(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.2 6.5.1.2] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l7b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1l7b RCSB], [http://www.ebi.ac.uk/pdbsum/1l7b PDBsum], [http://www.topsan.org/Proteins/NESGC/1l7b TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l7b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1l7b RCSB], [http://www.ebi.ac.uk/pdbsum/1l7b PDBsum], [http://www.topsan.org/Proteins/NESGC/1l7b TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DNLJ_THET8 DNLJ_THET8]] DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
| - | [[Category: Anderson, S | + | [[Category: Anderson, S]] |
| - | [[Category: Aramini, J | + | [[Category: Aramini, J]] |
| - | [[Category: Bhattacharya, D | + | [[Category: Bhattacharya, D]] |
| - | [[Category: Dixon, B L | + | [[Category: Dixon, B L]] |
| - | [[Category: Huang, Y P | + | [[Category: Huang, Y P]] |
| - | [[Category: Monleon, D | + | [[Category: Monleon, D]] |
| - | [[Category: Montelione, G T | + | [[Category: Montelione, G T]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Sahota, G | + | [[Category: Sahota, G]] |
| - | [[Category: Swapna, G V.T | + | [[Category: Swapna, G V.T]] |
| - | [[Category: Tejero, R | + | [[Category: Tejero, R]] |
| - | [[Category: Xiao, R | + | [[Category: Xiao, R]] |
| - | [[Category: Yin, C | + | [[Category: Yin, C]] |
[[Category: Autostructure]] | [[Category: Autostructure]] | ||
[[Category: Brct]] | [[Category: Brct]] | ||
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[[Category: Ligase]] | [[Category: Ligase]] | ||
[[Category: Nesg]] | [[Category: Nesg]] | ||
| - | [[Category: | + | [[Category: PSI, Protein structure initiative]] |
| - | + | ||
| - | + | ||
| - | + | ||
Revision as of 12:57, 25 December 2014
Solution NMR Structure of BRCT Domain of T. Thermophilus: Northeast Structural Genomics Consortium Target WR64TT
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Categories: Thermus thermophilus | Anderson, S | Aramini, J | Bhattacharya, D | Dixon, B L | Huang, Y P | Monleon, D | Montelione, G T | Structural genomic | Sahota, G | Swapna, G V.T | Tejero, R | Xiao, R | Yin, C | Autostructure | Brct | Dna ligase | Ligase | Nesg | PSI, Protein structure initiative
