1n22
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1n22]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salvia_officinalis Salvia officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1N22 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1n22]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salvia_officinalis Salvia officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1N22 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7A8:(1R)-DIMETHYL-(4-METHYL-CYCLOHEX-3-ENYL)-AMINE'>7A8</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7A8:(1R)-DIMETHYL-(4-METHYL-CYCLOHEX-3-ENYL)-AMINE'>7A8</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1n1b|1n1b]], [[1n1z|1n1z]], [[1n20|1n20]], [[1n21|1n21]], [[1n23|1n23]], [[1n24|1n24]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1n1b|1n1b]], [[1n1z|1n1z]], [[1n20|1n20]], [[1n21|1n21]], [[1n23|1n23]], [[1n24|1n24]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Bornyl_diphosphate_synthase Bornyl diphosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.5.1.8 5.5.1.8] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Bornyl_diphosphate_synthase Bornyl diphosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.5.1.8 5.5.1.8] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1n22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n22 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1n22 RCSB], [http://www.ebi.ac.uk/pdbsum/1n22 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1n22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n22 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1n22 RCSB], [http://www.ebi.ac.uk/pdbsum/1n22 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BPPS_SALOF BPPS_SALOF]] Catalyzes the formation of the (+)-camphor precursor (+)-bornyl diphosphate from geranyl diphosphate. The enzyme also produces significant amounts of (+)-alpha-pinene, (+)-camphene, and (+-)-limonene.<ref>PMID:9614092</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Bornyl diphosphate synthase]] | [[Category: Bornyl diphosphate synthase]] | ||
[[Category: Salvia officinalis]] | [[Category: Salvia officinalis]] | ||
| - | [[Category: Christianson, D W | + | [[Category: Christianson, D W]] |
| - | [[Category: Coates, R M | + | [[Category: Coates, R M]] |
| - | [[Category: Croteau, R B | + | [[Category: Croteau, R B]] |
| - | [[Category: Urbansky, M | + | [[Category: Urbansky, M]] |
| - | [[Category: Whittington, D A | + | [[Category: Whittington, D A]] |
| - | [[Category: Wise, M L | + | [[Category: Wise, M L]] |
[[Category: Isomerase]] | [[Category: Isomerase]] | ||
[[Category: Terpene synthase fold]] | [[Category: Terpene synthase fold]] | ||
Revision as of 14:47, 24 December 2014
(+)-Bornyl Diphosphate Synthase: Complex with Mg, pyrophosphate, and (4R)-7-aza-7,8-dihydrolimonene
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