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1l9l
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1l9l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L9L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L9L FirstGlance]. <br> | <table><tr><td colspan='2'>[[1l9l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L9L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L9L FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=MPO:3[N-MORPHOLINO]PROPANE+SULFONIC+ACID'>MPO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=MPO:3[N-MORPHOLINO]PROPANE+SULFONIC+ACID'>MPO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l9l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l9l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1l9l RCSB], [http://www.ebi.ac.uk/pdbsum/1l9l PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l9l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l9l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1l9l RCSB], [http://www.ebi.ac.uk/pdbsum/1l9l PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GNLY_HUMAN GNLY_HUMAN]] Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Anderson, D H | + | [[Category: Anderson, D H]] |
| - | [[Category: Cascio, D | + | [[Category: Cascio, D]] |
| - | [[Category: Eisenberg, D | + | [[Category: Eisenberg, D]] |
| - | [[Category: Ernst, W | + | [[Category: Ernst, W]] |
| - | [[Category: Krensky, A | + | [[Category: Krensky, A]] |
| - | [[Category: Modlin, R | + | [[Category: Modlin, R]] |
| - | [[Category: Sawaya, M R | + | [[Category: Sawaya, M R]] |
[[Category: Antimicrobial protein]] | [[Category: Antimicrobial protein]] | ||
[[Category: Granulysin]] | [[Category: Granulysin]] | ||
[[Category: Membrane-lytic]] | [[Category: Membrane-lytic]] | ||
[[Category: Saposin fold]] | [[Category: Saposin fold]] | ||
Revision as of 01:05, 25 December 2014
GRANULYSIN FROM HUMAN CYTOLYTIC T LYMPHOCYTES
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