1nk8
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1nk8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NK8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NK8 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1nk8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NK8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NK8 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SUC:SUCROSE'>SUC</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SUC:SUCROSE'>SUC</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1njw|1njw]], [[1njx|1njx]], [[1njy|1njy]], [[1njz|1njz]], [[1nk0|1nk0]], [[1nk4|1nk4]], [[1nk5|1nk5]], [[1nk6|1nk6]], [[1nk7|1nk7]], [[1nk9|1nk9]], [[1nkb|1nkb]], [[1nkc|1nkc]], [[1nke|1nke]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1njw|1njw]], [[1njx|1njx]], [[1njy|1njy]], [[1njz|1njz]], [[1nk0|1nk0]], [[1nk4|1nk4]], [[1nk5|1nk5]], [[1nk6|1nk6]], [[1nk7|1nk7]], [[1nk9|1nk9]], [[1nkb|1nkb]], [[1nkc|1nkc]], [[1nke|1nke]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nk8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nk8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nk8 RCSB], [http://www.ebi.ac.uk/pdbsum/1nk8 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nk8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nk8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nk8 RCSB], [http://www.ebi.ac.uk/pdbsum/1nk8 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DPO1_BACST DPO1_BACST]] In addition to polymerase activity, this DNA polymerase exhibits 5' to 3' exonuclease activity. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: DNA-directed DNA polymerase]] | [[Category: DNA-directed DNA polymerase]] | ||
[[Category: Geobacillus stearothermophilus]] | [[Category: Geobacillus stearothermophilus]] | ||
| - | [[Category: Beese, L S | + | [[Category: Beese, L S]] |
| - | [[Category: Johnson, S J | + | [[Category: Johnson, S J]] |
[[Category: Dna mismatch]] | [[Category: Dna mismatch]] | ||
[[Category: Dna polymerase i]] | [[Category: Dna polymerase i]] | ||
Revision as of 02:00, 25 December 2014
A BACILLUS DNA POLYMERASE I PRODUCT COMPLEX BOUND TO A GUANINE-THYMINE MISMATCH AFTER A SINGLE ROUND OF PRIMER EXTENSION, FOLLOWING INCORPORATION OF DCTP.
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