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1oni
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1oni]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ONI FirstGlance]. <br> | <table><tr><td colspan='2'>[[1oni]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ONI FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PSP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PSP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1oni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oni OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1oni RCSB], [http://www.ebi.ac.uk/pdbsum/1oni PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1oni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oni OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1oni RCSB], [http://www.ebi.ac.uk/pdbsum/1oni PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/UK114_HUMAN UK114_HUMAN]] Endoribonuclease responsible for the inhibition of the translation by cleaving mRNA. Inhibits cell-free protein synthesis. Cleaves phosphodiester bonds only in single-stranded RNA (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Delbrueck, H | + | [[Category: Delbrueck, H]] |
| - | [[Category: Erdmann, M F | + | [[Category: Erdmann, M F]] |
| - | [[Category: Heinemann, U | + | [[Category: Heinemann, U]] |
| - | [[Category: Manjasetty, B A | + | [[Category: Manjasetty, B A]] |
| - | [[Category: Mueller, U | + | [[Category: Mueller, U]] |
[[Category: Translation]] | [[Category: Translation]] | ||
[[Category: Translational inhibitor]] | [[Category: Translational inhibitor]] | ||
[[Category: Trichloroacetic acid soluble protein]] | [[Category: Trichloroacetic acid soluble protein]] | ||
[[Category: Yjgf/yer057c/uk114 family]] | [[Category: Yjgf/yer057c/uk114 family]] | ||
Revision as of 15:04, 25 December 2014
Crystal structure of a human p14.5, a translational inhibitor reveals different mode of ligand binding near the invariant residues of the Yjgf/UK114 protein family
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