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1xkt
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1xkt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XKT FirstGlance]. <br> | <table><tr><td colspan='2'>[[1xkt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XKT FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xkt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xkt RCSB], [http://www.ebi.ac.uk/pdbsum/1xkt PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xkt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xkt RCSB], [http://www.ebi.ac.uk/pdbsum/1xkt PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FAS_HUMAN FAS_HUMAN]] Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Chakravarty, B | + | [[Category: Chakravarty, B]] |
| - | [[Category: Chirala, S S | + | [[Category: Chirala, S S]] |
| - | [[Category: Gu, Z | + | [[Category: Gu, Z]] |
| - | [[Category: Quiocho, F A | + | [[Category: Quiocho, F A]] |
| - | [[Category: Wakil, S J | + | [[Category: Wakil, S J]] |
[[Category: Drug target]] | [[Category: Drug target]] | ||
[[Category: Human fatty acid synthase]] | [[Category: Human fatty acid synthase]] | ||
Revision as of 02:43, 25 December 2014
Human fatty acid synthase: Structure and substrate selectivity of the thioesterase domain
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