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1ov6

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ov6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OV6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OV6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ov6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OV6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OV6 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DBM:9-(6-DEOXY-BETA-D-ALLOFURANOSYL)-6-METHYLPURINE'>DBM</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DBM:9-(6-DEOXY-BETA-D-ALLOFURANOSYL)-6-METHYLPURINE'>DBM</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ecp|1ecp]], [[1a9o|1a9o]], [[1otx|1otx]], [[1oty|1oty]], [[1ou4|1ou4]], [[1oum|1oum]], [[1ovg|1ovg]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ecp|1ecp]], [[1a9o|1a9o]], [[1otx|1otx]], [[1oty|1oty]], [[1ou4|1ou4]], [[1oum|1oum]], [[1ovg|1ovg]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DEOD OR PUP OR B4384 OR Z5986 OR ECS5343 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DEOD OR PUP OR B4384 OR Z5986 OR ECS5343 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ov6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ov6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ov6 RCSB], [http://www.ebi.ac.uk/pdbsum/1ov6 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ov6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ov6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ov6 RCSB], [http://www.ebi.ac.uk/pdbsum/1ov6 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/DEOD_ECOLI DEOD_ECOLI]] Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules.[HAMAP-Rule:MF_01627]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Purine-nucleoside phosphorylase]]
[[Category: Purine-nucleoside phosphorylase]]
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[[Category: Allan, P W.]]
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[[Category: Allan, P W]]
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[[Category: Anand, R.]]
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[[Category: Anand, R]]
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[[Category: Bennett, E M.]]
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[[Category: Bennett, E M]]
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[[Category: Ealick, S E.]]
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[[Category: Ealick, S E]]
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[[Category: Hassan, A E.]]
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[[Category: Hassan, A E]]
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[[Category: McPherson, D T.]]
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[[Category: McPherson, D T]]
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[[Category: Parker, P W.]]
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[[Category: Parker, P W]]
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[[Category: Secrist, J A.]]
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[[Category: Secrist, J A]]
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[[Category: Sorscher, E J.]]
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[[Category: Sorscher, E J]]
[[Category: Allo]]
[[Category: Allo]]
[[Category: M64v]]
[[Category: M64v]]
[[Category: Mutant pnp]]
[[Category: Mutant pnp]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 07:01, 25 December 2014

M64V PNP + ALLO

1ov6, resolution 2.40Å

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