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1pgr

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1pgr]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PGR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PGR FirstGlance]. <br>
<table><tr><td colspan='2'>[[1pgr]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PGR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PGR FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pgr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pgr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1pgr RCSB], [http://www.ebi.ac.uk/pdbsum/1pgr PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pgr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pgr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1pgr RCSB], [http://www.ebi.ac.uk/pdbsum/1pgr PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CSF3_HUMAN CSF3_HUMAN]] Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. [[http://www.uniprot.org/uniprot/CSF3R_MOUSE CSF3R_MOUSE]] Receptor for granulocyte colony-stimulating factor (CSF3). In addition it may function in some adhesion or recognition events at the cell surface.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Aritomi, M.]]
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[[Category: Aritomi, M]]
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[[Category: Kunishima, N.]]
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[[Category: Kunishima, N]]
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[[Category: Kuroki, R.]]
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[[Category: Kuroki, R]]
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[[Category: Morikawa, K.]]
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[[Category: Morikawa, K]]
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[[Category: Okamoto, T.]]
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[[Category: Okamoto, T]]
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[[Category: Ota, Y.]]
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[[Category: Ota, Y]]
[[Category: Class1 cytokine]]
[[Category: Class1 cytokine]]
[[Category: Cytokine]]
[[Category: Cytokine]]
[[Category: Hematopoietic receptor]]
[[Category: Hematopoietic receptor]]
[[Category: Signal transduction]]
[[Category: Signal transduction]]

Revision as of 11:55, 25 December 2014

2:2 COMPLEX OF G-CSF WITH ITS RECEPTOR

1pgr, resolution 3.50Å

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