This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1p57

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1p57]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P57 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P57 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1p57]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P57 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P57 FirstGlance]. <br>
-
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CR4:2-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}BENZENOLATE'>CR4</scene><br>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CR4:2-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}BENZENOLATE'>CR4</scene></td></tr>
-
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p57 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1p57 RCSB], [http://www.ebi.ac.uk/pdbsum/1p57 PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p57 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1p57 RCSB], [http://www.ebi.ac.uk/pdbsum/1p57 PDBsum]</span></td></tr>
-
<table>
+
</table>
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/HEPS_HUMAN HEPS_HUMAN]] Plays an essential role in cell growth and maintenance of cell morphology. May mediate the activating cleavage of HGF and MST1/HGFL.<ref>PMID:21875933</ref> <ref>PMID:15839837</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 29: Line 31:
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Chan, H.]]
+
[[Category: Chan, H]]
-
[[Category: Ho, J D.]]
+
[[Category: Ho, J D]]
-
[[Category: Katz, B A.]]
+
[[Category: Katz, B A]]
-
[[Category: Luong, C.]]
+
[[Category: Luong, C]]
-
[[Category: McGrath, M E.]]
+
[[Category: McGrath, M E]]
-
[[Category: Mortara, K.]]
+
[[Category: Mortara, K]]
-
[[Category: Shrader, W D.]]
+
[[Category: Shrader, W D]]
-
[[Category: Somoza, J R.]]
+
[[Category: Somoza, J R]]
-
[[Category: Sperandio, D.]]
+
[[Category: Sperandio, D]]
-
[[Category: Sprengeler, P A.]]
+
[[Category: Sprengeler, P A]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Scavenger receptor cysteine-rich domain]]
[[Category: Scavenger receptor cysteine-rich domain]]
[[Category: Serine protease]]
[[Category: Serine protease]]
[[Category: Srcr]]
[[Category: Srcr]]

Revision as of 11:57, 25 December 2014

Extracellular domain of human hepsin

1p57, resolution 1.75Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools