1w6h
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1w6h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W6H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W6H FirstGlance]. <br> | <table><tr><td colspan='2'>[[1w6h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W6H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W6H FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TIT:N-((3S,4S)-5-[(4-BROMOBENZYL)OXY]-3-HYDROXY-4-{[N-(PYRIDIN-2-YLCARBONYL)-L-VALYL]AMINO}PENTANOYL)-L-ALANYL-L-LEUCINAMIDE'>TIT</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TIT:N-((3S,4S)-5-[(4-BROMOBENZYL)OXY]-3-HYDROXY-4-{[N-(PYRIDIN-2-YLCARBONYL)-L-VALYL]AMINO}PENTANOYL)-L-ALANYL-L-LEUCINAMIDE'>TIT</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1j8j|1j8j]], [[1lee|1lee]], [[1lf2|1lf2]], [[1lf3|1lf3]], [[1lf4|1lf4]], [[1m43|1m43]], [[1me6|1me6]], [[1pfz|1pfz]], [[1sme|1sme]], [[1w6i|1w6i]], [[1xdh|1xdh]], [[1xe5|1xe5]], [[1xe6|1xe6]], [[2bju|2bju]], [[2bl3|2bl3]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1j8j|1j8j]], [[1lee|1lee]], [[1lf2|1lf2]], [[1lf3|1lf3]], [[1lf4|1lf4]], [[1m43|1m43]], [[1me6|1me6]], [[1pfz|1pfz]], [[1sme|1sme]], [[1w6i|1w6i]], [[1xdh|1xdh]], [[1xe5|1xe5]], [[1xe6|1xe6]], [[2bju|2bju]], [[2bl3|2bl3]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Plasmepsin_II Plasmepsin II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.39 3.4.23.39] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Plasmepsin_II Plasmepsin II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.39 3.4.23.39] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w6h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1w6h RCSB], [http://www.ebi.ac.uk/pdbsum/1w6h PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w6h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1w6h RCSB], [http://www.ebi.ac.uk/pdbsum/1w6h PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 25: | Line 25: | ||
[[Category: Plasmepsin II]] | [[Category: Plasmepsin II]] | ||
[[Category: Plasmodium falciparum]] | [[Category: Plasmodium falciparum]] | ||
| - | [[Category: Johansson, P O | + | [[Category: Johansson, P O]] |
| - | [[Category: Kvarnstroem, I | + | [[Category: Kvarnstroem, I]] |
| - | [[Category: Lindberg, J | + | [[Category: Lindberg, J]] |
| - | [[Category: Rosenquist, A | + | [[Category: Rosenquist, A]] |
| - | [[Category: Samuelsson, B | + | [[Category: Samuelsson, B]] |
| - | [[Category: Unge, T | + | [[Category: Unge, T]] |
| - | [[Category: Vrang, L | + | [[Category: Vrang, L]] |
[[Category: Aspartic protease]] | [[Category: Aspartic protease]] | ||
[[Category: Drug]] | [[Category: Drug]] | ||
Revision as of 12:43, 6 January 2015
NOVEL PLASMEPSIN II-INHIBITOR COMPLEX
| |||||||||||
