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1tg6
From Proteopedia
(Difference between revisions)
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| + | <table cellpadding='5'><tr><td style='background-color: yellow;border:2px solid black;font-size:150%;'> | ||
| + | WARNING: This structure was flagged as problematic. For additional information see '''2014, October:''' at [[Retractions and Fraud]].</td></tr></table> | ||
==Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP== | ==Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP== | ||
<StructureSection load='1tg6' size='340' side='right' caption='[[1tg6]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='1tg6' size='340' side='right' caption='[[1tg6]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1tg6]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TG6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TG6 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1tg6]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TG6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TG6 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FME:N-FORMYLMETHIONINE'>FME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FME:N-FORMYLMETHIONINE'>FME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1tyf|1tyf]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1tyf|1tyf]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CLPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CLPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endopeptidase_Clp Endopeptidase Clp], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.92 3.4.21.92] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endopeptidase_Clp Endopeptidase Clp], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.92 3.4.21.92] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tg6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1tg6 RCSB], [http://www.ebi.ac.uk/pdbsum/1tg6 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tg6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1tg6 RCSB], [http://www.ebi.ac.uk/pdbsum/1tg6 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[Clp Protease|Clp Protease]] | *[[Clp Protease|Clp Protease]] | ||
| + | *[[Retractions and Fraud|Retractions and Fraud]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 36: | Line 39: | ||
[[Category: Endopeptidase Clp]] | [[Category: Endopeptidase Clp]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Ahvazi, B | + | [[Category: Ahvazi, B]] |
| - | [[Category: Kang, S G | + | [[Category: Kang, S G]] |
| - | [[Category: Maurizi, M R | + | [[Category: Maurizi, M R]] |
| - | [[Category: Mueser, T | + | [[Category: Mueser, T]] |
| - | [[Category: Thompson, M | + | [[Category: Thompson, M]] |
[[Category: Atp-dependent protease]] | [[Category: Atp-dependent protease]] | ||
[[Category: Clp/hsp 100]] | [[Category: Clp/hsp 100]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Mitochondrial clpp]] | [[Category: Mitochondrial clpp]] | ||
Revision as of 08:18, 18 November 2014
| WARNING: This structure was flagged as problematic. For additional information see 2014, October: at Retractions and Fraud. |
Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP
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