1wpw

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1wpw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_tokodaii Sulfolobus tokodaii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WPW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WPW FirstGlance]. <br>
<table><tr><td colspan='2'>[[1wpw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_tokodaii Sulfolobus tokodaii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WPW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WPW FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-isopropylmalate_dehydrogenase 3-isopropylmalate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.85 1.1.1.85] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-isopropylmalate_dehydrogenase 3-isopropylmalate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.85 1.1.1.85] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wpw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wpw RCSB], [http://www.ebi.ac.uk/pdbsum/1wpw PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wpw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wpw RCSB], [http://www.ebi.ac.uk/pdbsum/1wpw PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/LEU3_SULTO LEU3_SULTO]] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: 3-isopropylmalate dehydrogenase]]
[[Category: 3-isopropylmalate dehydrogenase]]
[[Category: Sulfolobus tokodaii]]
[[Category: Sulfolobus tokodaii]]
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[[Category: Hirose, R.]]
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[[Category: Hirose, R]]
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[[Category: Moriyama, H.]]
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[[Category: Moriyama, H]]
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[[Category: Oshima, T.]]
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[[Category: Oshima, T]]
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[[Category: Sakurai, M.]]
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[[Category: Sakurai, M]]
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[[Category: Sato, T.]]
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[[Category: Sato, T]]
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[[Category: Suzuki, T.]]
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[[Category: Suzuki, T]]
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[[Category: Tanaka, N.]]
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[[Category: Tanaka, N]]
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[[Category: Yamagishi, A.]]
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[[Category: Yamagishi, A]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]

Revision as of 16:30, 25 December 2014

Crystal Structure of IPMDH from Sulfolobus tokodaii

1wpw, resolution 2.80Å

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