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1ps8

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ps8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PS8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PS8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ps8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PS8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PS8 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nwc|1nwc]], [[1nwh|1nwh]], [[1nx6|1nx6]], [[1pqp|1pqp]], [[1pqu|1pqu]], [[1pu2|1pu2]], [[1pr3|1pr3]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nwc|1nwc]], [[1nwh|1nwh]], [[1nx6|1nx6]], [[1pqp|1pqp]], [[1pqu|1pqu]], [[1pu2|1pu2]], [[1pr3|1pr3]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">asd ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 Haemophilus influenzae])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">asd ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 Haemophilus influenzae])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aspartate-semialdehyde_dehydrogenase Aspartate-semialdehyde dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.11 1.2.1.11] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aspartate-semialdehyde_dehydrogenase Aspartate-semialdehyde dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.11 1.2.1.11] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ps8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ps8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ps8 RCSB], [http://www.ebi.ac.uk/pdbsum/1ps8 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ps8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ps8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ps8 RCSB], [http://www.ebi.ac.uk/pdbsum/1ps8 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/DHAS_HAEIN DHAS_HAEIN]] Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.<ref>PMID:12071715</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Aspartate-semialdehyde dehydrogenase]]
[[Category: Aspartate-semialdehyde dehydrogenase]]
[[Category: Haemophilus influenzae]]
[[Category: Haemophilus influenzae]]
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[[Category: Blanco, J.]]
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[[Category: Blanco, J]]
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[[Category: Coe, D M.]]
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[[Category: Coe, D M]]
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[[Category: Faehnle, C R.]]
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[[Category: Faehnle, C R]]
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[[Category: Moore, R A.]]
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[[Category: Moore, R A]]
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[[Category: Viola, R E.]]
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[[Category: Viola, R E]]
[[Category: Aspartate pathway]]
[[Category: Aspartate pathway]]
[[Category: Aspartate semialdehyde dehydrogenase]]
[[Category: Aspartate semialdehyde dehydrogenase]]
[[Category: Enzyme]]
[[Category: Enzyme]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]

Revision as of 14:28, 24 December 2014

Crystal Structure of the R270K Mutant of Aspartate Semialdehyde dehydrogenase from Haemophilus influenzae

1ps8, resolution 2.40Å

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