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1r4y

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1r4y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspergillus_giganteus Aspergillus giganteus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R4Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1R4Y FirstGlance]. <br>
<table><tr><td colspan='2'>[[1r4y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspergillus_giganteus Aspergillus giganteus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R4Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1R4Y FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1de3|1de3]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1de3|1de3]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SAR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5060 Aspergillus giganteus])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SAR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5060 Aspergillus giganteus])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_endonuclease rRNA endonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.10 3.1.27.10] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_endonuclease rRNA endonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.10 3.1.27.10] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1r4y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r4y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1r4y RCSB], [http://www.ebi.ac.uk/pdbsum/1r4y PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1r4y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r4y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1r4y RCSB], [http://www.ebi.ac.uk/pdbsum/1r4y PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RNAS_ASPGI RNAS_ASPGI]] Alpha-sarcin is specific for purines in both single- and double-stranded RNA. Its toxic action on eukaryotic cells is the result of cleavage of a single phosphodiester bond in the 60S subunit of ribosomes.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Ribonuclease|Ribonuclease]]
*[[Ribonuclease|Ribonuclease]]
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*[[Temp|Temp]]
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*[[User:Jaime.Prilusky/Test/tree|User:Jaime.Prilusky/Test/tree]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Aspergillus giganteus]]
[[Category: Aspergillus giganteus]]
[[Category: RRNA endonuclease]]
[[Category: RRNA endonuclease]]
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[[Category: Bruix, M.]]
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[[Category: Bruix, M]]
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[[Category: Garcia-Mayoral, M F.]]
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[[Category: Garcia-Mayoral, M F]]
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[[Category: Garcia-Ortega, L.]]
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[[Category: Garcia-Ortega, L]]
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[[Category: Gavilanes, J G.]]
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[[Category: Gavilanes, J G]]
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[[Category: Lillo, M P.]]
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[[Category: Lillo, M P]]
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[[Category: Pozo, A Martinez Del.]]
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[[Category: Pozo, A Martinez Del]]
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[[Category: Rico, M.]]
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[[Category: Rico, M]]
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[[Category: Santoro, J.]]
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[[Category: Santoro, J]]
[[Category: Alpha-beta protein]]
[[Category: Alpha-beta protein]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]

Revision as of 20:49, 24 December 2014

SOLUTION STRUCTURE OF THE DELETION MUTANT DELTA(7-22) OF THE CYTOTOXIC RIBONUCLEASE ALPHA-SARCIN

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