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1xwa
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1xwa]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XWA FirstGlance]. <br> | <table><tr><td colspan='2'>[[1xwa]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XWA FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xw9|1xw9]], [[1xwb|1xwb]], [[1xwc|1xwc]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xw9|1xw9]], [[1xwb|1xwb]], [[1xwc|1xwc]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TRX-2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TRX-2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xwa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xwa RCSB], [http://www.ebi.ac.uk/pdbsum/1xwa PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xwa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xwa RCSB], [http://www.ebi.ac.uk/pdbsum/1xwa PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/THIO2_DROME THIO2_DROME]] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1.<ref>PMID:11877442</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Drosophila melanogaster]] | [[Category: Drosophila melanogaster]] | ||
| - | [[Category: Becker, K | + | [[Category: Becker, K]] |
| - | [[Category: Hecker, B | + | [[Category: Hecker, B]] |
| - | [[Category: Irmler, A | + | [[Category: Irmler, A]] |
| - | [[Category: Schirmer, R H | + | [[Category: Schirmer, R H]] |
| - | [[Category: Wahl, M C | + | [[Category: Wahl, M C]] |
[[Category: Dimerization]] | [[Category: Dimerization]] | ||
| - | [[Category: Drosophila melanogaster]] | ||
[[Category: Electron transport]] | [[Category: Electron transport]] | ||
[[Category: Redox regulation]] | [[Category: Redox regulation]] | ||
[[Category: Thioredoxin]] | [[Category: Thioredoxin]] | ||
[[Category: X-ray crystal structure]] | [[Category: X-ray crystal structure]] | ||
Revision as of 16:04, 24 December 2014
Drospohila thioredoxin, oxidized, P41212
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