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1frv
From Proteopedia
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|PDB= 1frv |SIZE=350|CAPTION= <scene name='initialview01'>1frv</scene>, resolution 2.85Å | |PDB= 1frv |SIZE=350|CAPTION= <scene name='initialview01'>1frv</scene>, resolution 2.85Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene>, <scene name='pdbligand=FEL:HYDRATED+FE'>FEL</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/Cytochrome-c3_hydrogenase Cytochrome-c3 hydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.12.2.1 1.12.2.1] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytochrome-c3_hydrogenase Cytochrome-c3 hydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.12.2.1 1.12.2.1] </span> |
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1frv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1frv OCA], [http://www.ebi.ac.uk/pdbsum/1frv PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1frv RCSB]</span> | ||
}} | }} | ||
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[[Category: Frey, M.]] | [[Category: Frey, M.]] | ||
[[Category: Volbeda, A.]] | [[Category: Volbeda, A.]] | ||
| - | [[Category: F3S]] | ||
| - | [[Category: FEL]] | ||
| - | [[Category: NI]] | ||
| - | [[Category: SF4]] | ||
[[Category: ni-fe hydrogenase]] | [[Category: ni-fe hydrogenase]] | ||
[[Category: oxidoreductase]] | [[Category: oxidoreductase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:29:01 2008'' |
Revision as of 17:29, 30 March 2008
| |||||||
| , resolution 2.85Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , , | ||||||
| Activity: | Cytochrome-c3 hydrogenase, with EC number 1.12.2.1 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
CRYSTAL STRUCTURE OF THE OXIDIZED FORM OF NI-FE HYDROGENASE
Overview
The X-ray structure of the heterodimeric Ni-Fe hydrogenase from Desulfovibrio gigas, the enzyme responsible for the metabolism of molecular hydrogen, has been solved at 2.85 A resolution. The active site, which appears to contain, besides nickel, a second metal ion, is buried in the 60K subunit. The 28K subunit, which coordinates one [3Fe-4S] and two [4Fe-4S] clusters, contains an amino-terminal domain with similarities to the redox protein flavodoxin. The structure suggests plausible electron and proton transfer pathways.
About this Structure
1FRV is a Protein complex structure of sequences from Desulfovibrio gigas. Full crystallographic information is available from OCA.
Reference
Crystal structure of the nickel-iron hydrogenase from Desulfovibrio gigas., Volbeda A, Charon MH, Piras C, Hatchikian EC, Frey M, Fontecilla-Camps JC, Nature. 1995 Feb 16;373(6515):580-7. PMID:7854413
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