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1pk5
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1pk5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PK5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PK5 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1pk5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PK5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PK5 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NR5A2 OR LRH1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NR5A2 OR LRH1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pk5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1pk5 RCSB], [http://www.ebi.ac.uk/pdbsum/1pk5 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pk5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1pk5 RCSB], [http://www.ebi.ac.uk/pdbsum/1pk5 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NR5A2_MOUSE NR5A2_MOUSE]] Binds to promoters containing the sequence element 5'-AACGACCGACCTTGAG-3'. Plays a role in the regulation of gene expression in liver and pancreas. May play a role in embryonic development (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Fletterick, R J | + | [[Category: Fletterick, R J]] |
| - | [[Category: Ingraham, H A | + | [[Category: Ingraham, H A]] |
| - | [[Category: Krylova, I N | + | [[Category: Krylova, I N]] |
| - | [[Category: Sablin, E P | + | [[Category: Sablin, E P]] |
[[Category: Gene regulation]] | [[Category: Gene regulation]] | ||
[[Category: Ligand-binding domain]] | [[Category: Ligand-binding domain]] | ||
[[Category: Lrh-1]] | [[Category: Lrh-1]] | ||
[[Category: Nuclear receptor]] | [[Category: Nuclear receptor]] | ||
Revision as of 22:11, 25 December 2014
Crystal structure of the orphan nuclear receptor LRH-1
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