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2joo
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2joo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JOO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JOO FirstGlance]. <br> | <table><tr><td colspan='2'>[[2joo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JOO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JOO FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2joo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2joo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2joo RCSB], [http://www.ebi.ac.uk/pdbsum/2joo PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2joo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2joo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2joo RCSB], [http://www.ebi.ac.uk/pdbsum/2joo PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ITH1_HIRME ITH1_HIRME]] Hirudin is a potent thrombin-specific protease inhibitor. It forms a stable non-covalent complex with alpha-thrombin, thereby abolishing its ability to cleave fibrinogen.<ref>PMID:17585879</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Hirudo medicinalis]] | [[Category: Hirudo medicinalis]] | ||
| - | [[Category: Dai, L | + | [[Category: Dai, L]] |
| - | [[Category: Liu, X | + | [[Category: Liu, X]] |
| - | [[Category: Mo, W | + | [[Category: Mo, W]] |
| - | [[Category: Song, H | + | [[Category: Song, H]] |
| - | [[Category: Song, X | + | [[Category: Song, X]] |
| - | [[Category: Yan, X | + | [[Category: Yan, X]] |
[[Category: Blood clotting]] | [[Category: Blood clotting]] | ||
[[Category: Mainly beta]] | [[Category: Mainly beta]] | ||
Revision as of 07:12, 24 December 2014
The NMR Solution Structure of Recombinant RGD-hirudin
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Categories: Hirudo medicinalis | Dai, L | Liu, X | Mo, W | Song, H | Song, X | Yan, X | Blood clotting | Mainly beta
