2h03
From Proteopedia
(Difference between revisions)
Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2h03]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H03 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H03 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2h03]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H03 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H03 FirstGlance]. <br> | ||
- | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3UN:(4-{4-[(TERT-BUTOXYCARBONYL)AMINO]-2,2-BIS(ETHOXYCARBONYL)BUTYL}PHENYL)SULFAMIC+ACID'>3UN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3UN:(4-{4-[(TERT-BUTOXYCARBONYL)AMINO]-2,2-BIS(ETHOXYCARBONYL)BUTYL}PHENYL)SULFAMIC+ACID'>3UN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
- | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ho2|2ho2]], [[2ho4|2ho4]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ho2|2ho2]], [[2ho4|2ho4]]</td></tr> |
- | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTPRB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTPRB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
- | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr> |
- | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h03 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h03 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2h03 RCSB], [http://www.ebi.ac.uk/pdbsum/2h03 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h03 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h03 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2h03 RCSB], [http://www.ebi.ac.uk/pdbsum/2h03 PDBsum]</span></td></tr> |
- | <table> | + | </table> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Line 36: | Line 36: | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein-tyrosine-phosphatase]] | [[Category: Protein-tyrosine-phosphatase]] | ||
- | [[Category: Amarasinghe, K D | + | [[Category: Amarasinghe, K D]] |
- | [[Category: Clark, C M | + | [[Category: Clark, C M]] |
- | [[Category: Evdokimov, A G | + | [[Category: Evdokimov, A G]] |
- | [[Category: Gray, J L | + | [[Category: Gray, J L]] |
- | [[Category: Maier, M B | + | [[Category: Maier, M B]] |
- | [[Category: Mekel, M | + | [[Category: Mekel, M]] |
- | [[Category: Nichols, R | + | [[Category: Nichols, R]] |
- | [[Category: Peters, K G | + | [[Category: Peters, K G]] |
- | [[Category: Pokross, M E | + | [[Category: Pokross, M E]] |
- | [[Category: Walter, R L | + | [[Category: Walter, R L]] |
[[Category: Drug design]] | [[Category: Drug design]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] |
Revision as of 08:22, 16 January 2015
Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors
|
Categories: Homo sapiens | Protein-tyrosine-phosphatase | Amarasinghe, K D | Clark, C M | Evdokimov, A G | Gray, J L | Maier, M B | Mekel, M | Nichols, R | Peters, K G | Pokross, M E | Walter, R L | Drug design | Hydrolase | Inhibitor | Phosphatase | Protein tyrosine phosphatase | Sulfamic acid | Wpd-loop