2cio

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2cio]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Carica_papaya Carica papaya] and [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CIO FirstGlance]. <br>
<table><tr><td colspan='2'>[[2cio]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Carica_papaya Carica papaya] and [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CIO FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bp4|1bp4]], [[1bqi|1bqi]], [[1cvz|1cvz]], [[1eff|1eff]], [[1khp|1khp]], [[1khq|1khq]], [[1pad|1pad]], [[1pe6|1pe6]], [[1pip|1pip]], [[1pop|1pop]], [[1ppd|1ppd]], [[1ppn|1ppn]], [[1ppp|1ppp]], [[1stf|1stf]], [[2pad|2pad]], [[4pad|4pad]], [[5pad|5pad]], [[6pad|6pad]], [[9pap|9pap]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bp4|1bp4]], [[1bqi|1bqi]], [[1cvz|1cvz]], [[1eff|1eff]], [[1khp|1khp]], [[1khq|1khq]], [[1pad|1pad]], [[1pe6|1pe6]], [[1pip|1pip]], [[1pop|1pop]], [[1ppd|1ppd]], [[1ppn|1ppn]], [[1ppp|1ppp]], [[1stf|1stf]], [[2pad|2pad]], [[4pad|4pad]], [[5pad|5pad]], [[6pad|6pad]], [[9pap|9pap]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Papain Papain], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.2 3.4.22.2] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Papain Papain], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.2 3.4.22.2] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cio RCSB], [http://www.ebi.ac.uk/pdbsum/2cio PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cio RCSB], [http://www.ebi.ac.uk/pdbsum/2cio PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Papain]]
[[Category: Papain]]
[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
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[[Category: Alphey, M S.]]
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[[Category: Alphey, M S]]
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[[Category: Hunter, W N.]]
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[[Category: Hunter, W N]]
[[Category: Allergen]]
[[Category: Allergen]]
[[Category: Complex hydrolase-inhibitor]]
[[Category: Complex hydrolase-inhibitor]]
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[[Category: Protease]]
[[Category: Protease]]
[[Category: Thiol protease]]
[[Category: Thiol protease]]
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[[Category: Trypanosoma brucei]]
 
[[Category: Zymogen]]
[[Category: Zymogen]]

Revision as of 17:45, 15 January 2015

THE HIGH RESOLUTION X-RAY STRUCTURE OF PAPAIN COMPLEXED WITH FRAGMENTS OF THE TRYPANOSOMA BRUCEI CYSTEINE PROTEASE INHIBITOR ICP.

2cio, resolution 1.50Å

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