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2j7k
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2j7k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J7K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J7K FirstGlance]. <br> | <table><tr><td colspan='2'>[[2j7k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J7K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J7K FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GCP:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>GCP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GCP:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>GCP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fnm|1fnm]], [[1ip8|1ip8]], [[1ipm|1ipm]], [[1ipo|1ipo]], [[1ipr|1ipr]], [[1jqm|1jqm]], [[1jqs|1jqs]], [[1ktv|1ktv]], [[1pn6|1pn6]], [[2bcw|2bcw]], [[2bm0|2bm0]], [[2bm1|2bm1]], [[2bv3|2bv3]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fnm|1fnm]], [[1ip8|1ip8]], [[1ipm|1ipm]], [[1ipo|1ipo]], [[1ipr|1ipr]], [[1jqm|1jqm]], [[1jqs|1jqs]], [[1ktv|1ktv]], [[1pn6|1pn6]], [[2bcw|2bcw]], [[2bm0|2bm0]], [[2bm1|2bm1]], [[2bv3|2bv3]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-synthesizing_GTPase Protein-synthesizing GTPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.5.3 3.6.5.3] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-synthesizing_GTPase Protein-synthesizing GTPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.5.3 3.6.5.3] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j7k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2j7k RCSB], [http://www.ebi.ac.uk/pdbsum/2j7k PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j7k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2j7k RCSB], [http://www.ebi.ac.uk/pdbsum/2j7k PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/EFG_THETH EFG_THETH]] Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Protein-synthesizing GTPase]] | [[Category: Protein-synthesizing GTPase]] | ||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
| - | [[Category: Hansson, S | + | [[Category: Hansson, S]] |
| - | [[Category: Logan, D T | + | [[Category: Logan, D T]] |
[[Category: Elongation factor]] | [[Category: Elongation factor]] | ||
[[Category: Gtp-binding]] | [[Category: Gtp-binding]] | ||
Revision as of 04:47, 25 December 2014
CRYSTAL STRUCTURE OF THE T84A MUTANT EF-G:GDPCP COMPLEX
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