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2kiu
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2kiu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KIU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KIU FirstGlance]. <br> | <table><tr><td colspan='2'>[[2kiu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KIU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KIU FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">3p14.1, FOXP1, HSPC215 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">3p14.1, FOXP1, HSPC215 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kiu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kiu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kiu RCSB], [http://www.ebi.ac.uk/pdbsum/2kiu PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kiu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kiu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kiu RCSB], [http://www.ebi.ac.uk/pdbsum/2kiu PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/FOXP1_HUMAN FOXP1_HUMAN]] MALT lymphoma;Precursor B-cell acute lymphoblastic leukemia;Intellectual disability-severe speech delay-mild dysmorphism syndrome. A chromosomal aberration involving FOXP1 is found in acute lymphoblastic leukemia. Translocation t(9;3)(p13;p14.1) with PAX5. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:20950788</ref> | [[http://www.uniprot.org/uniprot/FOXP1_HUMAN FOXP1_HUMAN]] MALT lymphoma;Precursor B-cell acute lymphoblastic leukemia;Intellectual disability-severe speech delay-mild dysmorphism syndrome. A chromosomal aberration involving FOXP1 is found in acute lymphoblastic leukemia. Translocation t(9;3)(p13;p14.1) with PAX5. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:20950788</ref> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Chu, Y | + | [[Category: Chu, Y]] |
| - | [[Category: Chuang, W | + | [[Category: Chuang, W]] |
[[Category: Dna binding protein]] | [[Category: Dna binding protein]] | ||
[[Category: Dna-binding]] | [[Category: Dna-binding]] | ||
Revision as of 13:57, 19 January 2015
Solution structure and backbone dynamics of the DNA-binding domain of FOXP1: Insight into its domain swapping
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