2f0h

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2f0h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F0H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F0H FirstGlance]. <br>
<table><tr><td colspan='2'>[[2f0h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F0H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F0H FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ey0|1ey0]], [[2exz|2exz]], [[2ey1|2ey1]], [[2ey2|2ey2]], [[2ey5|2ey5]], [[2ey6|2ey6]], [[2eyf|2eyf]], [[2eyh|2eyh]], [[2eyj|2eyj]], [[2eyl|2eyl]], [[2eym|2eym]], [[2eyo|2eyo]], [[2eyp|2eyp]], [[2f0d|2f0d]], [[2f0e|2f0e]], [[2f0f|2f0f]], [[2f0g|2f0g]], [[2f0i|2f0i]], [[2f0j|2f0j]], [[2f0k|2f0k]], [[2f0l|2f0l]], [[2f0m|2f0m]], [[2f0n|2f0n]], [[2f0o|2f0o]], [[2f0p|2f0p]], [[2f0q|2f0q]], [[2f0s|2f0s]], [[2f0t|2f0t]], [[2f0u|2f0u]], [[2f0v|2f0v]], [[2f0w|2f0w]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ey0|1ey0]], [[2exz|2exz]], [[2ey1|2ey1]], [[2ey2|2ey2]], [[2ey5|2ey5]], [[2ey6|2ey6]], [[2eyf|2eyf]], [[2eyh|2eyh]], [[2eyj|2eyj]], [[2eyl|2eyl]], [[2eym|2eym]], [[2eyo|2eyo]], [[2eyp|2eyp]], [[2f0d|2f0d]], [[2f0e|2f0e]], [[2f0f|2f0f]], [[2f0g|2f0g]], [[2f0i|2f0i]], [[2f0j|2f0j]], [[2f0k|2f0k]], [[2f0l|2f0l]], [[2f0m|2f0m]], [[2f0n|2f0n]], [[2f0o|2f0o]], [[2f0p|2f0p]], [[2f0q|2f0q]], [[2f0s|2f0s]], [[2f0t|2f0t]], [[2f0u|2f0u]], [[2f0v|2f0v]], [[2f0w|2f0w]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nuc ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nuc ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f0h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f0h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f0h RCSB], [http://www.ebi.ac.uk/pdbsum/2f0h PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f0h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f0h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f0h RCSB], [http://www.ebi.ac.uk/pdbsum/2f0h PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU]] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Micrococcal nuclease]]
[[Category: Micrococcal nuclease]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: Lu, J Z.]]
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[[Category: Lu, J Z]]
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[[Category: Sakon, J.]]
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[[Category: Sakon, J]]
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[[Category: Stites, W E.]]
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[[Category: Stites, W E]]
[[Category: Calcium]]
[[Category: Calcium]]
[[Category: Dna hydrolase]]
[[Category: Dna hydrolase]]

Revision as of 18:07, 25 December 2014

Crystal structure of Staphylococcal nuclease mutant V66L

2f0h, resolution 2.15Å

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