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2fsi

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2fsi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FSI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FSI FirstGlance]. <br>
<table><tr><td colspan='2'>[[2fsi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FSI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FSI FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1tf5|1tf5]], [[1m6n|1m6n]], [[1nl3|1nl3]], [[2fsf|2fsf]], [[2fsg|2fsg]], [[2fsh|2fsh]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1tf5|1tf5]], [[1m6n|1m6n]], [[1nl3|1nl3]], [[2fsf|2fsf]], [[2fsg|2fsg]], [[2fsh|2fsh]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">secA, azi, pea, prlD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">secA, azi, pea, prlD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fsi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fsi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fsi RCSB], [http://www.ebi.ac.uk/pdbsum/2fsi PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fsi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fsi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fsi RCSB], [http://www.ebi.ac.uk/pdbsum/2fsi PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/SECA_ECOLI SECA_ECOLI]] Required for protein export, interacts with the SecYEG preprotein conducting channel. SecA has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.<ref>PMID:15140892</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Economou, A.]]
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[[Category: Economou, A]]
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[[Category: Papanikolau, Y.]]
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[[Category: Papanikolau, Y]]
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[[Category: Petratos, K.]]
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[[Category: Petratos, K]]
[[Category: Atpase]]
[[Category: Atpase]]
[[Category: Dna-rna helicase]]
[[Category: Dna-rna helicase]]

Revision as of 14:19, 25 December 2014

Complex SecA:ADP from Escherichia coli

2fsi, resolution 2.11Å

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