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2ux1
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ux1]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_suis Streptococcus suis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UX1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UX1 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2ux1]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_suis Streptococcus suis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UX1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UX1 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1umn|1umn]], [[2bw1|2bw1]], [[2cf7|2cf7]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1umn|1umn]], [[2bw1|2bw1]], [[2cf7|2cf7]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ux1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ux1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ux1 RCSB], [http://www.ebi.ac.uk/pdbsum/2ux1 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ux1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ux1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ux1 RCSB], [http://www.ebi.ac.uk/pdbsum/2ux1 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DPS_STRSU DPS_STRSU]] Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction (By similarity). It binds and incorporates Fe(2+) iron. Is responsible for hydrogen peroxide resistance. Does not bind DNA. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Streptococcus suis]] | [[Category: Streptococcus suis]] | ||
| - | [[Category: Finne, J | + | [[Category: Finne, J]] |
| - | [[Category: Haataja, S | + | [[Category: Haataja, S]] |
| - | [[Category: Havukainen, H | + | [[Category: Havukainen, H]] |
| - | [[Category: Kauko, A | + | [[Category: Kauko, A]] |
| - | [[Category: Meyer-Klaucke, W | + | [[Category: Meyer-Klaucke, W]] |
| - | [[Category: Papageorgiou, A C | + | [[Category: Papageorgiou, A C]] |
| - | [[Category: Pulliainen, A T | + | [[Category: Pulliainen, A T]] |
[[Category: Metal-binding]] | [[Category: Metal-binding]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
Revision as of 02:40, 25 December 2014
IDENTIFICATION OF TWO ZINC-BINDING SITES IN THE STREPTOCOCCUS SUIS DPR PROTEIN
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