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2qs9
From Proteopedia
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2qs9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QS9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QS9 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2qs9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QS9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QS9 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RBBP9, BOG, RBBP10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RBBP9, BOG, RBBP10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qs9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qs9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qs9 RCSB], [http://www.ebi.ac.uk/pdbsum/2qs9 PDBsum], [http://www.topsan.org/Proteins/NESGC/2qs9 TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qs9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qs9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qs9 RCSB], [http://www.ebi.ac.uk/pdbsum/2qs9 PDBsum], [http://www.topsan.org/Proteins/NESGC/2qs9 TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RBBP9_HUMAN RBBP9_HUMAN]] May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta1 through interaction with retinoblastoma and the subsequent displacement of E2F-1. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Acton, T B | + | [[Category: Acton, T B]] |
| - | [[Category: Chen, C X | + | [[Category: Chen, C X]] |
| - | [[Category: Cunningham, K | + | [[Category: Cunningham, K]] |
| - | [[Category: Hunt, J F | + | [[Category: Hunt, J F]] |
| - | [[Category: Kuzin, A | + | [[Category: Kuzin, A]] |
| - | [[Category: Maglaqui, M | + | [[Category: Maglaqui, M]] |
| - | [[Category: Montelione, G T | + | [[Category: Montelione, G T]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Owens, L | + | [[Category: Owens, L]] |
| - | [[Category: Seetharaman, J | + | [[Category: Seetharaman, J]] |
| - | [[Category: Su, M | + | [[Category: Su, M]] |
| - | [[Category: Tong, L | + | [[Category: Tong, L]] |
| - | [[Category: Vorobiev, S M | + | [[Category: Vorobiev, S M]] |
| - | [[Category: Xiao, R | + | [[Category: Xiao, R]] |
[[Category: B5t overexpressed gene protein]] | [[Category: B5t overexpressed gene protein]] | ||
[[Category: Bog]] | [[Category: Bog]] | ||
[[Category: Hr2978]] | [[Category: Hr2978]] | ||
[[Category: Nesg]] | [[Category: Nesg]] | ||
| - | [[Category: Northeast structural genomics consortium]] | ||
[[Category: Nucleus]] | [[Category: Nucleus]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
| - | [[Category: Protein structure initiative | + | [[Category: PSI, Protein structure initiative]] |
| - | + | ||
[[Category: Rbbp10]] | [[Category: Rbbp10]] | ||
[[Category: Rbbp9]] | [[Category: Rbbp9]] | ||
[[Category: Retinoblastoma-binding protein 10]] | [[Category: Retinoblastoma-binding protein 10]] | ||
[[Category: Retinoblastoma-binding protein 9]] | [[Category: Retinoblastoma-binding protein 9]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Structural protein]] | [[Category: Structural protein]] | ||
Revision as of 06:53, 24 December 2014
Crystal structure of the human retinoblastoma-binding protein 9 (RBBP-9). NESG target HR2978
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Categories: Homo sapiens | Acton, T B | Chen, C X | Cunningham, K | Hunt, J F | Kuzin, A | Maglaqui, M | Montelione, G T | Structural genomic | Owens, L | Seetharaman, J | Su, M | Tong, L | Vorobiev, S M | Xiao, R | B5t overexpressed gene protein | Bog | Hr2978 | Nesg | Nucleus | Phosphorylation | PSI, Protein structure initiative | Rbbp10 | Rbbp9 | Retinoblastoma-binding protein 10 | Retinoblastoma-binding protein 9 | Structural protein

