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2vaz

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2vaz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VAZ FirstGlance]. <br>
<table><tr><td colspan='2'>[[2vaz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VAZ FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1p6g|1p6g]], [[1p87|1p87]], [[2avy|2avy]], [[2aw7|2aw7]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1p6g|1p6g]], [[1p87|1p87]], [[2avy|2avy]], [[2aw7|2aw7]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vaz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vaz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vaz RCSB], [http://www.ebi.ac.uk/pdbsum/2vaz PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vaz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vaz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vaz RCSB], [http://www.ebi.ac.uk/pdbsum/2vaz PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RS15_ECOLI RS15_ECOLI]] One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.[HAMAP-Rule:MF_01343] In the E.coli 70S ribosome it has been modeled (PubMed:12809609) to contact the 23S rRNA of the 50S subunit forming part of bridge B4. In the two 3.5 A resolved ribosome structures (PubMed:16272117) there are minor differences between side-chain conformations.[HAMAP-Rule:MF_01343]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Ehresmann, C.]]
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[[Category: Ehresmann, C]]
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[[Category: Klaholz, B P.]]
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[[Category: Klaholz, B P]]
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[[Category: Marzi, S.]]
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[[Category: Marzi, S]]
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[[Category: Myasnikov, A G.]]
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[[Category: Myasnikov, A G]]
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[[Category: Romby, P.]]
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[[Category: Romby, P]]
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[[Category: Serganov, A.]]
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[[Category: Serganov, A]]
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[[Category: Yusupov, M.]]
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[[Category: Yusupov, M]]
[[Category: Gene expression regulation]]
[[Category: Gene expression regulation]]
[[Category: Mrna structure]]
[[Category: Mrna structure]]

Revision as of 21:32, 25 December 2014

Model of the S15-mRNA complex fitted into the cryo-EM map of the 70S entrapment complex.

2vaz, resolution 10.00Å

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