2r24
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2r24]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R24 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R24 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2r24]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R24 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R24 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LDT:IDD594'>LDT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LDT:IDD594'>LDT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r24 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2r24 RCSB], [http://www.ebi.ac.uk/pdbsum/2r24 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r24 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2r24 RCSB], [http://www.ebi.ac.uk/pdbsum/2r24 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN]] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Aldehyde reductase]] | [[Category: Aldehyde reductase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Afonine, P | + | [[Category: Afonine, P]] |
| - | [[Category: Blakeley, M P | + | [[Category: Blakeley, M P]] |
| - | [[Category: Cachau, R | + | [[Category: Cachau, R]] |
| - | [[Category: Cousido-Siah, A | + | [[Category: Cousido-Siah, A]] |
| - | [[Category: Ginell, S | + | [[Category: Ginell, S]] |
| - | [[Category: Haertlein, M | + | [[Category: Haertlein, M]] |
| - | [[Category: Hazemann, I | + | [[Category: Hazemann, I]] |
| - | [[Category: Joachimiak, A | + | [[Category: Joachimiak, A]] |
| - | [[Category: Meilleur, F | + | [[Category: Meilleur, F]] |
| - | [[Category: Mitschler, A | + | [[Category: Mitschler, A]] |
| - | [[Category: Myles, D | + | [[Category: Myles, D]] |
| - | [[Category: Podjarny, A | + | [[Category: Podjarny, A]] |
| - | [[Category: Ruiz, F | + | [[Category: Ruiz, F]] |
| - | [[Category: Ventura, O N | + | [[Category: Ventura, O N]] |
[[Category: Beta/alpha-8 tim barrel]] | [[Category: Beta/alpha-8 tim barrel]] | ||
[[Category: Cataract]] | [[Category: Cataract]] | ||
[[Category: Nadp]] | [[Category: Nadp]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
Revision as of 23:00, 24 December 2014
Human Aldose Reductase structure
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Categories: Aldehyde reductase | Homo sapiens | Afonine, P | Blakeley, M P | Cachau, R | Cousido-Siah, A | Ginell, S | Haertlein, M | Hazemann, I | Joachimiak, A | Meilleur, F | Mitschler, A | Myles, D | Podjarny, A | Ruiz, F | Ventura, O N | Beta/alpha-8 tim barrel | Cataract | Nadp | Oxidoreductase
