3bpu
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3bpu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BPU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BPU FirstGlance]. <br> | <table><tr><td colspan='2'>[[3bpu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BPU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BPU FirstGlance]. <br> | ||
- | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
- | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAGI1, BAIAP1, BAP1, TNRC19 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAGI1, BAIAP1, BAP1, TNRC19 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
- | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bpu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bpu RCSB], [http://www.ebi.ac.uk/pdbsum/3bpu PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bpu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bpu RCSB], [http://www.ebi.ac.uk/pdbsum/3bpu PDBsum]</span></td></tr> |
- | <table> | + | </table> |
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/MAGI1_HUMAN MAGI1_HUMAN]] May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Arrowsmith, C H | + | [[Category: Arrowsmith, C H]] |
- | [[Category: Cooper, C | + | [[Category: Cooper, C]] |
- | [[Category: Delft, F von | + | [[Category: Delft, F von]] |
- | [[Category: Doyle, D A | + | [[Category: Doyle, D A]] |
- | [[Category: Edwards, A M | + | [[Category: Edwards, A M]] |
- | [[Category: Elkins, J | + | [[Category: Elkins, J]] |
- | [[Category: Hozjan, V | + | [[Category: Hozjan, V]] |
- | [[Category: Oppermann, U | + | [[Category: Oppermann, U]] |
- | [[Category: Pike, A C.W | + | [[Category: Pike, A C.W]] |
- | [[Category: Pilka, E S | + | [[Category: Pilka, E S]] |
- | [[Category: | + | [[Category: Structural genomic]] |
- | [[Category: Weigelt, J | + | [[Category: Weigelt, J]] |
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Cell junction]] | [[Category: Cell junction]] | ||
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[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
- | [[Category: Structural genomics consortium]] | ||
[[Category: Tight junction]] | [[Category: Tight junction]] | ||
[[Category: Transferase]] | [[Category: Transferase]] |
Revision as of 10:15, 25 December 2014
Crystal structure of the 3rd PDZ domain of human membrane associated guanylate kinase, C677S and C709S double mutant
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Categories: Homo sapiens | Arrowsmith, C H | Cooper, C | Delft, F von | Doyle, D A | Edwards, A M | Elkins, J | Hozjan, V | Oppermann, U | Pike, A C.W | Pilka, E S | Structural genomic | Weigelt, J | Atp-binding | Cell junction | Membrane associated guanylate kinase | Nucleotide-binding | Pdz | Phosphoprotein | Sgc | Tight junction | Transferase