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2q7g

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2q7g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanosarcina_mazei Methanosarcina mazei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q7G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Q7G FirstGlance]. <br>
<table><tr><td colspan='2'>[[2q7g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanosarcina_mazei Methanosarcina mazei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q7G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Q7G FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CCL:N~6~-[(CYCLOPENTYLOXY)CARBONYL]-D-LYSINE'>CCL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CCL:N~6~-[(CYCLOPENTYLOXY)CARBONYL]-D-LYSINE'>CCL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2q7e|2q7e]], [[2q7h|2q7h]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2q7e|2q7e]], [[2q7h|2q7h]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pylS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2209 Methanosarcina mazei])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pylS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2209 Methanosarcina mazei])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q7g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2q7g RCSB], [http://www.ebi.ac.uk/pdbsum/2q7g PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q7g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2q7g RCSB], [http://www.ebi.ac.uk/pdbsum/2q7g PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PYLS_METMA PYLS_METMA]] Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Methanosarcina mazei]]
[[Category: Methanosarcina mazei]]
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[[Category: Kavran, J M.]]
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[[Category: Kavran, J M]]
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[[Category: Steitz, T A.]]
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[[Category: Steitz, T A]]
[[Category: Ligase]]
[[Category: Ligase]]
[[Category: Pyrrolysine]]
[[Category: Pyrrolysine]]
[[Category: Pyrrolysyl-trna syntethetase]]
[[Category: Pyrrolysyl-trna syntethetase]]

Revision as of 14:34, 25 December 2014

Pyrrolysine tRNA Synthetase bound to a pyrrolysine analogue (cyc) and ATP

2q7g, resolution 1.90Å

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