2q9v

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2q9v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q9V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Q9V FirstGlance]. <br>
<table><tr><td colspan='2'>[[2q9v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q9V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Q9V FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAGI1, BAIAP1, BAP1, TNRC19 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAGI1, BAIAP1, BAP1, TNRC19 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q9v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2q9v RCSB], [http://www.ebi.ac.uk/pdbsum/2q9v PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q9v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2q9v RCSB], [http://www.ebi.ac.uk/pdbsum/2q9v PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MAGI1_HUMAN MAGI1_HUMAN]] May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C A.]]
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[[Category: Arrowsmith, C A]]
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[[Category: Cooper, C.]]
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[[Category: Cooper, C]]
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[[Category: Delft, F von.]]
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[[Category: Delft, F von]]
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[[Category: Doyle, D A.]]
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[[Category: Doyle, D A]]
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[[Category: Edwards, A.]]
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[[Category: Edwards, A]]
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[[Category: Elkins, J M.]]
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[[Category: Elkins, J M]]
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[[Category: Hozjan, V.]]
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[[Category: Hozjan, V]]
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[[Category: Kavanagh, K L.]]
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[[Category: Kavanagh, K L]]
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[[Category: Oppermann, U.]]
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[[Category: Oppermann, U]]
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[[Category: Papagrigoriou, E.]]
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[[Category: Papagrigoriou, E]]
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[[Category: Pilka, E S.]]
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[[Category: Pilka, E S]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Structural genomic]]
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[[Category: Sundstrom, M.]]
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[[Category: Sundstrom, M]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt, J]]
[[Category: Cys ser mutant]]
[[Category: Cys ser mutant]]
[[Category: Membrane associated guanylate kinase]]
[[Category: Membrane associated guanylate kinase]]
[[Category: Pdz]]
[[Category: Pdz]]
[[Category: Sgc]]
[[Category: Sgc]]
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[[Category: Structural genomics consortium]]
 
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 10:43, 25 December 2014

Crystal structure of the C890S mutant of the 4th PDZ domain of human membrane associated guanylate kinase

2q9v, resolution 2.00Å

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