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2nov
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2nov]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NOV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NOV FirstGlance]. <br> | <table><tr><td colspan='2'>[[2nov]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NOV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NOV FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">parC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1313 Streptococcus pneumoniae])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">parC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1313 Streptococcus pneumoniae])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2nov FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nov OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2nov RCSB], [http://www.ebi.ac.uk/pdbsum/2nov PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2nov FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nov OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2nov RCSB], [http://www.ebi.ac.uk/pdbsum/2nov PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PARC_STRPN PARC_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Streptococcus pneumoniae]] | [[Category: Streptococcus pneumoniae]] | ||
| - | [[Category: Achari, A | + | [[Category: Achari, A]] |
| - | [[Category: Ferrara, J D | + | [[Category: Ferrara, J D]] |
| - | [[Category: Fisher, L M | + | [[Category: Fisher, L M]] |
| - | [[Category: Laponogov, I | + | [[Category: Laponogov, I]] |
| - | [[Category: Pan, X S | + | [[Category: Pan, X S]] |
| - | [[Category: Sanderson, M R | + | [[Category: Sanderson, M R]] |
| - | [[Category: Sohi, M K | + | [[Category: Sohi, M K]] |
| - | [[Category: Veselkov, D A | + | [[Category: Veselkov, D A]] |
| - | [[Category: Yang, C | + | [[Category: Yang, C]] |
[[Category: Dna binding]] | [[Category: Dna binding]] | ||
[[Category: Dna cleavage]] | [[Category: Dna cleavage]] | ||
Revision as of 16:44, 24 December 2014
Breakage-reunion domain of S.pneumoniae topo IV: crystal structure of a gram-positive quinolone target
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