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2bkr

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2bkr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BKR FirstGlance]. <br>
<table><tr><td colspan='2'>[[2bkr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BKR FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ndd|1ndd]], [[1r4m|1r4m]], [[1r4n|1r4n]], [[1xt9|1xt9]], [[2bkq|2bkq]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ndd|1ndd]], [[1r4m|1r4m]], [[1r4n|1r4n]], [[1xt9|1xt9]], [[2bkq|2bkq]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bkr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bkr RCSB], [http://www.ebi.ac.uk/pdbsum/2bkr PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bkr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bkr RCSB], [http://www.ebi.ac.uk/pdbsum/2bkr PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/SENP8_HUMAN SENP8_HUMAN]] Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.<ref>PMID:12730221</ref> <ref>PMID:12759363</ref> <ref>PMID:12759362</ref> <ref>PMID:15242646</ref> <ref>PMID:15775960</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Dong, C.]]
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[[Category: Dong, C]]
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[[Category: Hay, R T.]]
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[[Category: Hay, R T]]
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[[Category: Liu, H.]]
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[[Category: Liu, H]]
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[[Category: Naismith, J H.]]
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[[Category: Naismith, J H]]
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[[Category: Shen, L N.]]
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[[Category: Shen, L N]]
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[[Category: Xirodimas, D.]]
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[[Category: Xirodimas, D]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Protease]]
[[Category: Protease]]

Revision as of 11:03, 25 December 2014

NEDD8 NEDP1 COMPLEX

2bkr, resolution 1.90Å

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