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3i5i

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3i5i]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Doryteuthis_pealeii Doryteuthis pealeii] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ekw 2ekw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3I5I FirstGlance]. <br>
<table><tr><td colspan='2'>[[3i5i]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Doryteuthis_pealeii Doryteuthis pealeii] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ekw 2ekw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3I5I FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ekw|2ekw]], [[3i5f|3i5f]], [[3i5g|3i5g]], [[3i5h|3i5h]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ekw|2ekw]], [[3i5f|3i5f]], [[3i5g|3i5g]], [[3i5h|3i5h]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3i5i RCSB], [http://www.ebi.ac.uk/pdbsum/3i5i PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3i5i RCSB], [http://www.ebi.ac.uk/pdbsum/3i5i PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MLE_TODPA MLE_TODPA]] In molluscan muscle, calcium regulation is associated with myosin rather than with actin. Muscle myosin contains two types of light chains: the catalytic light chain, essential for ATPase activity, and the regulatory light chain, a calcium-binding protein responsible for Ca(2+) dependent binding and Ca(2+) dependent Mg-ATPase activity. [[http://www.uniprot.org/uniprot/MLR_TODPA MLR_TODPA]] In molluscan muscle, calcium regulation is associated with myosin rather than with actin. Muscle myosin contains two types of light chains: the catalytic light chain, essential for ATPase activity, and the regulatory light chain, a calcium-binding protein responsible for Ca(2+) dependent binding and Ca(2+) dependent Mg-ATPase activity.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Doryteuthis pealeii]]
[[Category: Doryteuthis pealeii]]
[[Category: Todarodes pacificus]]
[[Category: Todarodes pacificus]]
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[[Category: Brown, J H.]]
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[[Category: Brown, J H]]
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[[Category: Cohen, C.]]
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[[Category: Cohen, C]]
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[[Category: Gourinath, S.]]
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[[Category: Gourinath, S]]
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[[Category: Himmel, D M.]]
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[[Category: Himmel, D M]]
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[[Category: Kovacs, M.]]
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[[Category: Kovacs, M]]
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[[Category: Neall-Hennessey, E O.]]
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[[Category: Neall-Hennessey, E O]]
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[[Category: Nyitray, L.]]
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[[Category: Nyitray, L]]
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[[Category: Reshetnikova, L.]]
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[[Category: Reshetnikova, L]]
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[[Category: Reutzel, R.]]
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[[Category: Reutzel, R]]
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[[Category: Szent-Gyorgyi, A G.]]
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[[Category: Szent-Gyorgyi, A G]]
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[[Category: Yang, Y.]]
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[[Category: Yang, Y]]
[[Category: Contractile protein]]
[[Category: Contractile protein]]
[[Category: Myosin s1]]
[[Category: Myosin s1]]

Revision as of 07:00, 25 December 2014

The crystal structure of squid myosin S1 in the presence of SO4 2-

3i5i, resolution 3.30Å

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