3hid
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3hid]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis_co92 Yersinia pestis co92]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HID OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HID FirstGlance]. <br> | <table><tr><td colspan='2'>[[3hid]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis_co92 Yersinia pestis co92]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HID OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HID FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG6:1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE'>PG6</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG6:1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE'>PG6</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gi:16120713, purA, y0635, YPO0378, YP_0534 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=214092 Yersinia pestis CO92])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gi:16120713, purA, y0635, YPO0378, YP_0534 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=214092 Yersinia pestis CO92])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenylosuccinate_synthase Adenylosuccinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.4 6.3.4.4] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenylosuccinate_synthase Adenylosuccinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.4 6.3.4.4] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hid OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hid RCSB], [http://www.ebi.ac.uk/pdbsum/3hid PDBsum], [http://www.topsan.org/Proteins/CSGID/3hid TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hid OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hid RCSB], [http://www.ebi.ac.uk/pdbsum/3hid PDBsum], [http://www.topsan.org/Proteins/CSGID/3hid TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PURA_YERPE PURA_YERPE]] Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Adenylosuccinate synthase]] | [[Category: Adenylosuccinate synthase]] | ||
[[Category: Yersinia pestis co92]] | [[Category: Yersinia pestis co92]] | ||
| - | [[Category: Anderson, W | + | [[Category: Anderson, W]] |
| - | [[Category: Joachimiak, A | + | [[Category: Joachimiak, A]] |
| - | [[Category: Peterson, S | + | [[Category: Peterson, S]] |
| - | [[Category: Zhang, R | + | [[Category: Zhang, R]] |
| - | [[Category: Zhou, M | + | [[Category: Zhou, M]] |
[[Category: Adenylosuccinate synthetase]] | [[Category: Adenylosuccinate synthetase]] | ||
| - | [[Category: | + | [[Category: Structural genomic]] |
[[Category: Csgid]] | [[Category: Csgid]] | ||
[[Category: Gtp-binding]] | [[Category: Gtp-binding]] | ||
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[[Category: Magnesium]] | [[Category: Magnesium]] | ||
[[Category: Metal-binding]] | [[Category: Metal-binding]] | ||
| - | [[Category: Niaid structural genomic]] | ||
[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Pura]] | [[Category: Pura]] | ||
Revision as of 15:36, 25 December 2014
Crystal structure of adenylosuccinate synthetase from Yersinia pestis CO92
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Categories: Adenylosuccinate synthase | Yersinia pestis co92 | Anderson, W | Joachimiak, A | Peterson, S | Zhang, R | Zhou, M | Adenylosuccinate synthetase | Structural genomic | Csgid | Gtp-binding | Ligase | Magnesium | Metal-binding | Nucleotide-binding | Pura | Purine biosynthesis | Purine ribonucleotide biosynthesis | Virulence associated factor
