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3k2i
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3k2i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K2I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3K2I FirstGlance]. <br> | <table><tr><td colspan='2'>[[3k2i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K2I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3K2I FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ACOT4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ACOT4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Palmitoyl-CoA_hydrolase Palmitoyl-CoA hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.2.2 3.1.2.2] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Palmitoyl-CoA_hydrolase Palmitoyl-CoA hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.2.2 3.1.2.2] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k2i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k2i RCSB], [http://www.ebi.ac.uk/pdbsum/3k2i PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k2i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k2i RCSB], [http://www.ebi.ac.uk/pdbsum/3k2i PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ACOT4_HUMAN ACOT4_HUMAN]] Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (By similarity). Succinyl-CoA thioesterase that also hydrolyzes long chain saturated and unsaturated monocarboxylic acyl-CoAs. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Palmitoyl-CoA hydrolase]] | [[Category: Palmitoyl-CoA hydrolase]] | ||
| - | [[Category: Arrowsmith, C H | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Berg, S Van Den | + | [[Category: Berg, S Van Den]] |
| - | [[Category: Berglund, H | + | [[Category: Berglund, H]] |
| - | [[Category: Bountra, C | + | [[Category: Bountra, C]] |
| - | [[Category: Collins, R | + | [[Category: Collins, R]] |
| - | [[Category: Edwards, A M | + | [[Category: Edwards, A M]] |
| - | [[Category: Flodin, S | + | [[Category: Flodin, S]] |
| - | [[Category: Flores, A | + | [[Category: Flores, A]] |
| - | [[Category: Graslund, S | + | [[Category: Graslund, S]] |
| - | [[Category: Hammarstrom, M | + | [[Category: Hammarstrom, M]] |
| - | [[Category: Johansson, A | + | [[Category: Johansson, A]] |
| - | [[Category: Johansson, I | + | [[Category: Johansson, I]] |
| - | [[Category: Kallas, A | + | [[Category: Kallas, A]] |
| - | [[Category: Karlberg, T | + | [[Category: Karlberg, T]] |
| - | [[Category: Kotenyova, T | + | [[Category: Kotenyova, T]] |
| - | [[Category: Kotzsch, A | + | [[Category: Kotzsch, A]] |
| - | [[Category: Kraulis, P | + | [[Category: Kraulis, P]] |
| - | [[Category: Markova, N | + | [[Category: Markova, N]] |
| - | [[Category: Moche, M | + | [[Category: Moche, M]] |
| - | [[Category: Nielsen, T K | + | [[Category: Nielsen, T K]] |
| - | [[Category: Nordlund, P | + | [[Category: Nordlund, P]] |
| - | [[Category: Nyman, T | + | [[Category: Nyman, T]] |
| - | [[Category: Persson, C | + | [[Category: Persson, C]] |
| - | [[Category: Roos, A K | + | [[Category: Roos, A K]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Schuler, H | + | [[Category: Schuler, H]] |
| - | [[Category: Schutz, P | + | [[Category: Schutz, P]] |
| - | [[Category: Siponen, M I | + | [[Category: Siponen, M I]] |
| - | [[Category: Svensson, L | + | [[Category: Svensson, L]] |
| - | [[Category: Thorsell, A G | + | [[Category: Thorsell, A G]] |
| - | [[Category: Tresaugues, L | + | [[Category: Tresaugues, L]] |
| - | [[Category: Wahlberg, E | + | [[Category: Wahlberg, E]] |
| - | [[Category: Weigelt, J | + | [[Category: Weigelt, J]] |
| - | [[Category: Welin, M | + | [[Category: Welin, M]] |
| - | [[Category: Wisniewska, M | + | [[Category: Wisniewska, M]] |
[[Category: Alpha/beta hydrolase fold seven-stranded beta-sandwich]] | [[Category: Alpha/beta hydrolase fold seven-stranded beta-sandwich]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| Line 65: | Line 67: | ||
[[Category: Serine esterase]] | [[Category: Serine esterase]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Structural genomics consortium]] | ||
Revision as of 08:47, 25 December 2014
Human Acyl-coenzyme A thioesterase 4
| |||||||||||
Categories: Homo sapiens | Palmitoyl-CoA hydrolase | Arrowsmith, C H | Berg, S Van Den | Berglund, H | Bountra, C | Collins, R | Edwards, A M | Flodin, S | Flores, A | Graslund, S | Hammarstrom, M | Johansson, A | Johansson, I | Kallas, A | Karlberg, T | Kotenyova, T | Kotzsch, A | Kraulis, P | Markova, N | Moche, M | Nielsen, T K | Nordlund, P | Nyman, T | Persson, C | Roos, A K | Structural genomic | Schuler, H | Schutz, P | Siponen, M I | Svensson, L | Thorsell, A G | Tresaugues, L | Wahlberg, E | Weigelt, J | Welin, M | Wisniewska, M | Alpha/beta hydrolase fold seven-stranded beta-sandwich | Hydrolase | Peroxisome | Serine esterase | Sgc
