3drw

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3drw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DRW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DRW FirstGlance]. <br>
<table><tr><td colspan='2'>[[3drw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DRW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DRW FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1u2x|1u2x]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1u2x|1u2x]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pfkC, PH1645 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=53953 Pyrococcus horikoshii])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pfkC, PH1645 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=53953 Pyrococcus horikoshii])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ADP-specific_phosphofructokinase ADP-specific phosphofructokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.146 2.7.1.146] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ADP-specific_phosphofructokinase ADP-specific phosphofructokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.146 2.7.1.146] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3drw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3drw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3drw RCSB], [http://www.ebi.ac.uk/pdbsum/3drw PDBsum], [http://www.topsan.org/Proteins/MCSG/3drw TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3drw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3drw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3drw RCSB], [http://www.ebi.ac.uk/pdbsum/3drw PDBsum], [http://www.topsan.org/Proteins/MCSG/3drw TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/K6PF_PYRHO K6PF_PYRHO]] Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: ADP-specific phosphofructokinase]]
[[Category: ADP-specific phosphofructokinase]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
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[[Category: Brown, G.]]
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[[Category: Brown, G]]
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[[Category: Cuff, M E.]]
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[[Category: Cuff, M E]]
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[[Category: Edwards, A M.]]
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[[Category: Edwards, A M]]
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[[Category: Jia, Z.]]
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[[Category: Jia, Z]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak, A]]
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[[Category: Kochinyan, S.]]
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[[Category: Kochinyan, S]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Structural genomic]]
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[[Category: Savchenko, A.]]
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[[Category: Savchenko, A]]
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[[Category: Singer, A U.]]
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[[Category: Singer, A U]]
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[[Category: Skarina, T.]]
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[[Category: Skarina, T]]
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[[Category: Yakunin, A F.]]
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[[Category: Yakunin, A F]]
[[Category: 6-phosphofructokinase]]
[[Category: 6-phosphofructokinase]]
[[Category: Adp]]
[[Category: Adp]]
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[[Category: Mcsg]]
[[Category: Mcsg]]
[[Category: Metal-binding]]
[[Category: Metal-binding]]
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[[Category: Midwest center for structural genomic]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Pyrococcus horikoshii]]
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[[Category: Structural genomic]]
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[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 17:12, 24 December 2014

Crystal Structure of a Phosphofructokinase from Pyrococcus horikoshii OT3 with AMP

3drw, resolution 1.90Å

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OCA

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