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1e80

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1e80]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E80 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1E80 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1e80]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E80 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1E80 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0GQ:4-AMINO-N-{(1R,8R,9R,13R)-16-(4-AMINO-2-METHYLPYRIMIDIN-5-YL)-1-BENZYL-8-(CYCLOHEXYLMETHYL)-9-HYDROXY-13-[(1S)-1-METHYLPROPYL]-2,6,11,14-TETRAOXO-3,7,12,15-TETRAAZAHEXADEC-1-YL}PIPERIDINE-1-CARBOXAMIDE'>0GQ</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0GQ:4-AMINO-N-{(1R,8R,9R,13R)-16-(4-AMINO-2-METHYLPYRIMIDIN-5-YL)-1-BENZYL-8-(CYCLOHEXYLMETHYL)-9-HYDROXY-13-[(1S)-1-METHYLPROPYL]-2,6,11,14-TETRAOXO-3,7,12,15-TETRAAZAHEXADEC-1-YL}PIPERIDINE-1-CARBOXAMIDE'>0GQ</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ape|4ape]], [[1e5o|1e5o]], [[1e81|1e81]], [[1e82|1e82]], [[1eed|1eed]], [[1ent|1ent]], [[2er0|2er0]], [[4er1|4er1]], [[5er1|5er1]], [[4er2|4er2]], [[5er2|5er2]], [[3er3|3er3]], [[4er4|4er4]], [[3er5|3er5]], [[2er6|2er6]], [[2er7|2er7]], [[1er8|1er8]], [[2er9|2er9]], [[1epl|1epl]], [[1epm|1epm]], [[1epn|1epn]], [[1epo|1epo]], [[1epp|1epp]], [[1epq|1epq]], [[1epr|1epr]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ape|4ape]], [[1e5o|1e5o]], [[1e81|1e81]], [[1e82|1e82]], [[1eed|1eed]], [[1ent|1ent]], [[2er0|2er0]], [[4er1|4er1]], [[5er1|5er1]], [[4er2|4er2]], [[5er2|5er2]], [[3er3|3er3]], [[4er4|4er4]], [[3er5|3er5]], [[2er6|2er6]], [[2er7|2er7]], [[1er8|1er8]], [[2er9|2er9]], [[1epl|1epl]], [[1epm|1epm]], [[1epn|1epn]], [[1epo|1epo]], [[1epp|1epp]], [[1epq|1epq]], [[1epr|1epr]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mucorpepsin Mucorpepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.23 3.4.23.23] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mucorpepsin Mucorpepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.23 3.4.23.23] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1e80 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e80 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1e80 RCSB], [http://www.ebi.ac.uk/pdbsum/1e80 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1e80 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e80 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1e80 RCSB], [http://www.ebi.ac.uk/pdbsum/1e80 PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Cryphonectria parasitica]]
[[Category: Cryphonectria parasitica]]
[[Category: Mucorpepsin]]
[[Category: Mucorpepsin]]
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[[Category: Cooper, J B.]]
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[[Category: Cooper, J B]]
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[[Category: Raddatz, P.]]
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[[Category: Raddatz, P]]
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[[Category: Read, J A.]]
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[[Category: Read, J A]]
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[[Category: Rippmann, F.]]
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[[Category: Rippmann, F]]
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[[Category: Toldo, L.]]
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[[Category: Toldo, L]]
[[Category: Acid proteinase]]
[[Category: Acid proteinase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Hydrolase-hydrolase inhibitor complex]]

Revision as of 19:17, 22 December 2014

Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD56133

1e80, resolution 2.05Å

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