1qo0

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1qo0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QO0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1qo0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QO0 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMD:BUTYRAMIDE'>BMD</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMD:BUTYRAMIDE'>BMD</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1pea|1pea]], [[1qnl|1qnl]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1pea|1pea]], [[1qnl|1qnl]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qo0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qo0 RCSB], [http://www.ebi.ac.uk/pdbsum/1qo0 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qo0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qo0 RCSB], [http://www.ebi.ac.uk/pdbsum/1qo0 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/AMIC_PSEAE AMIC_PSEAE]] Negatively regulates the expression of the aliphatic amidase operon. AmiC functions by inhibiting the action of AmiR at the protein level. It exhibits protein kinase activity. [[http://www.uniprot.org/uniprot/AMIR_PSEAE AMIR_PSEAE]] Positive controlling element of AmiE, the gene for aliphatic amidase. Acts as a transcriptional antitermination factor. It is thought to allow RNA polymerase read through a rho-independent transcription terminator between the AmiE promoter and gene.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: Hara, B P.O.]]
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[[Category: Hara, B P.O]]
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[[Category: Pearl, L H.]]
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[[Category: Pearl, L H]]
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[[Category: Roe, S M.]]
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[[Category: Roe, S M]]
[[Category: Binding protein]]
[[Category: Binding protein]]
[[Category: Gene regulator]]
[[Category: Gene regulator]]
[[Category: Receptor]]
[[Category: Receptor]]

Revision as of 08:19, 24 December 2014

AMIDE RECEPTOR OF THE AMIDASE OPERON OF PSEUDOMONAS AERUGINOSA (AMIC) COMPLEXED WITH THE POSITIVE REGULATOR AMIR.

1qo0, resolution 2.25Å

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