1nq7
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1nq7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NQ7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NQ7 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1nq7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NQ7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NQ7 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARL:7-(3,5-DITERT-BUTYLPHENYL)-3-METHYLOCTA-2,4,6-TRIENOIC+ACID'>ARL</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARL:7-(3,5-DITERT-BUTYLPHENYL)-3-METHYLOCTA-2,4,6-TRIENOIC+ACID'>ARL</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NR1F2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NR1F2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nq7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nq7 RCSB], [http://www.ebi.ac.uk/pdbsum/1nq7 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nq7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nq7 RCSB], [http://www.ebi.ac.uk/pdbsum/1nq7 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RORB_RAT RORB_RAT]] Orphan nuclear receptor required for normal postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5'-AGGTCA-3' in the OPN1SW promoter. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
| - | [[Category: Dorsselaer, A Van | + | [[Category: Dorsselaer, A Van]] |
| - | [[Category: Moras, D | + | [[Category: Moras, D]] |
| - | [[Category: Renaud, J P | + | [[Category: Renaud, J P]] |
| - | [[Category: Sanglier, S | + | [[Category: Sanglier, S]] |
| - | [[Category: Schuele, R | + | [[Category: Schuele, R]] |
| - | [[Category: Stehlin-Gaon, C | + | [[Category: Stehlin-Gaon, C]] |
| - | [[Category: Willmann, D | + | [[Category: Willmann, D]] |
[[Category: Antagonist]] | [[Category: Antagonist]] | ||
[[Category: Ligand-binding domain]] | [[Category: Ligand-binding domain]] | ||
Revision as of 23:20, 24 December 2014
Characterization of ligands for the orphan nuclear receptor RORbeta
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