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1gws

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|PDB= 1gws |SIZE=350|CAPTION= <scene name='initialview01'>1gws</scene>, resolution 2.40&Aring;
|PDB= 1gws |SIZE=350|CAPTION= <scene name='initialview01'>1gws</scene>, resolution 2.40&Aring;
|SITE= <scene name='pdbsite=AC1:Hec+Binding+Site+For+Residue+A+616'>AC1</scene>
|SITE= <scene name='pdbsite=AC1:Hec+Binding+Site+For+Residue+A+616'>AC1</scene>
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|LIGAND= <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene> and <scene name='pdbligand=HEC:HEME C'>HEC</scene>
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|LIGAND= <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>
|ACTIVITY=
|ACTIVITY=
|GENE=
|GENE=
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|DOMAIN=
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gws OCA], [http://www.ebi.ac.uk/pdbsum/1gws PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1gws RCSB]</span>
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[[Category: Czjzek, M.]]
[[Category: Czjzek, M.]]
[[Category: Haser, R.]]
[[Category: Haser, R.]]
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[[Category: HEC]]
 
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[[Category: HEM]]
 
[[Category: electron transport]]
[[Category: electron transport]]
[[Category: heme]]
[[Category: heme]]
[[Category: multiheme cytochrome]]
[[Category: multiheme cytochrome]]
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[[Category: periplasmic]]
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[[Category: periplasmic,repeat]]
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[[Category: repeat]]
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[[Category: signal]]
[[Category: signal]]
[[Category: sulfate reducing bacteria]]
[[Category: sulfate reducing bacteria]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:29:01 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:52:58 2008''

Revision as of 17:53, 30 March 2008


PDB ID 1gws

Drag the structure with the mouse to rotate
, resolution 2.40Å
Sites:
Ligands: ,
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



HEXADECAHEME HIGH MOLECULAR WEIGHT CYTOCHROME HMC FROM DESULFOVIBRIO VULGARIS HILDENBOROUGH


Overview

Sulfate-reducing bacteria contain a variety of multi-heme c-type cytochromes. The cytochrome of highest molecular weight (Hmc) contains 16 heme groups and is part of a transmembrane complex involved in the sulfate respiration pathway. We present the 2.42 A resolution crystal structure of the Desulfovibrio vulgaris Hildenborough cytochrome Hmc and a structural model of the complex with its physiological electron transfer partner, cytochrome c(3), obtained by NMR restrained soft-docking calculations. The Hmc is composed of three domains, which exist independently in different sulfate-reducing species, namely cytochrome c(3), cytochrome c(7), and Hcc. The complex involves the last heme at the C-terminal region of the V-shaped Hmc and heme 4 of cytochrome c(3), and represents an example for specific cytochrome-cytochrome interaction.

About this Structure

1GWS is a Single protein structure of sequence from Desulfovibrio vulgaris. Full crystallographic information is available from OCA.

Reference

The crystal structure of the hexadeca-heme cytochrome Hmc and a structural model of its complex with cytochrome c(3)., Czjzek M, ElAntak L, Zamboni V, Morelli X, Dolla A, Guerlesquin F, Bruschi M, Structure. 2002 Dec;10(12):1677-86. PMID:12467575

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