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1qtf
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1qtf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QTF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QTF FirstGlance]. <br> | <table><tr><td colspan='2'>[[1qtf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QTF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QTF FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qtf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qtf RCSB], [http://www.ebi.ac.uk/pdbsum/1qtf PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qtf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qtf RCSB], [http://www.ebi.ac.uk/pdbsum/1qtf PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ETB_STAAU ETB_STAAU]] Has serine protease-like properties and binds to the skin protein profilaggrin. Cleaves substrates after acidic residues. Exfoliative toxins cause impetigous diseases commonly referred as staphylococcal scalded skin syndrome (SSSS).<ref>PMID:2117445</ref> <ref>PMID:2384148</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Staphylococcus aureus]] | [[Category: Staphylococcus aureus]] | ||
| - | [[Category: Earhart, C A | + | [[Category: Earhart, C A]] |
| - | [[Category: Monie, D D | + | [[Category: Monie, D D]] |
| - | [[Category: Ohlendorf, D H | + | [[Category: Ohlendorf, D H]] |
| - | [[Category: Schlievert, P M | + | [[Category: Schlievert, P M]] |
| - | [[Category: Vath, G M | + | [[Category: Vath, G M]] |
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
[[Category: Superantigen]] | [[Category: Superantigen]] | ||
[[Category: Toxin]] | [[Category: Toxin]] | ||
Revision as of 17:09, 25 December 2014
CRYSTAL STRUCTURE OF EXFOLIATIVE TOXIN B
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