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1odn

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1odn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Emericella_nidulans Emericella nidulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ODN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ODN FirstGlance]. <br>
<table><tr><td colspan='2'>[[1odn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Emericella_nidulans Emericella nidulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ODN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ODN FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=APV:6-(5-AMINO-5-CARBOXY-PENTANOYLAMINO)-3-HYDROXYMETHYL-7-OXO-4-THIA-1-AZA-BICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC+ACID'>APV</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=APV:6-(5-AMINO-5-CARBOXY-PENTANOYLAMINO)-3-HYDROXYMETHYL-7-OXO-4-THIA-1-AZA-BICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC+ACID'>APV</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bk0|1bk0]], [[1blz|1blz]], [[1hb1|1hb1]], [[1hb2|1hb2]], [[1hb3|1hb3]], [[1hb4|1hb4]], [[1ips|1ips]], [[1obn|1obn]], [[1odm|1odm]], [[1oc1|1oc1]], [[1qiq|1qiq]], [[1qje|1qje]], [[1qjf|1qjf]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bk0|1bk0]], [[1blz|1blz]], [[1hb1|1hb1]], [[1hb2|1hb2]], [[1hb3|1hb3]], [[1hb4|1hb4]], [[1ips|1ips]], [[1obn|1obn]], [[1odm|1odm]], [[1oc1|1oc1]], [[1qiq|1qiq]], [[1qje|1qje]], [[1qjf|1qjf]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1odn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1odn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1odn RCSB], [http://www.ebi.ac.uk/pdbsum/1odn PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1odn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1odn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1odn RCSB], [http://www.ebi.ac.uk/pdbsum/1odn PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/IPNS_EMENI IPNS_EMENI]] Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Emericella nidulans]]
[[Category: Emericella nidulans]]
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[[Category: Adlington, R M.]]
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[[Category: Adlington, R M]]
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[[Category: Baldwin, J E.]]
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[[Category: Baldwin, J E]]
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[[Category: Burzlaff, N I.]]
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[[Category: Burzlaff, N I]]
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[[Category: Clifton, I J.]]
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[[Category: Clifton, I J]]
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[[Category: Elkins, J M.]]
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[[Category: Elkins, J M]]
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[[Category: Roach, P L.]]
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[[Category: Roach, P L]]
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[[Category: Rutledge, P J.]]
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[[Category: Rutledge, P J]]
[[Category: Antibiotic biosynthesis]]
[[Category: Antibiotic biosynthesis]]
[[Category: B-lactam antibiotic]]
[[Category: B-lactam antibiotic]]

Revision as of 15:19, 24 December 2014

ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (OXYGEN-EXPOSED PRODUCT FROM ANAEROBIC AC-VINYLGLYCINE FE COMPLEX)

1odn, resolution 1.60Å

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