1mnn

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1mnn]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MNN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MNN FirstGlance]. <br>
<table><tr><td colspan='2'>[[1mnn]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MNN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MNN FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mn4|1mn4]], [[1m7u|1m7u]], [[1m6u|1m6u]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mn4|1mn4]], [[1m7u|1m7u]], [[1m6u|1m6u]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NDT80 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NDT80 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mnn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mnn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1mnn RCSB], [http://www.ebi.ac.uk/pdbsum/1mnn PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mnn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mnn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1mnn RCSB], [http://www.ebi.ac.uk/pdbsum/1mnn PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/NDT80_YEAST NDT80_YEAST]] Transcription factor required for successful completion of meiosis and spore formation. Gets activated after completion of meiotic recombination at the end of prophase I. Recognizes and binds to the middle sporulation element (MSE) 5'-C[AG]CAAA[AT]-3' in the promoter region of stage-specific genes that are required for progression through meiosis and sporulation. Competes for binding to MSE with the transcriptional repressor SUM1, which represses middle sporulation-specific genes during mitosis and early sporulation.<ref>PMID:8524222</ref> <ref>PMID:9660952</ref> <ref>PMID:9742092</ref> <ref>PMID:12832469</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Glover, J N.]]
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[[Category: Glover, J N]]
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[[Category: Lamoureux, J S.]]
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[[Category: Lamoureux, J S]]
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[[Category: Stuart, D.]]
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[[Category: Stuart, D]]
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[[Category: Tsang, R.]]
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[[Category: Tsang, R]]
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[[Category: Wu, C.]]
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[[Category: Wu, C]]
[[Category: Ig fold]]
[[Category: Ig fold]]
[[Category: Protein_dna complex]]
[[Category: Protein_dna complex]]
[[Category: Transcription-dna complex]]
[[Category: Transcription-dna complex]]

Revision as of 15:25, 24 December 2014

Structure of the sporulation specific transcription factor Ndt80 bound to DNA

1mnn, resolution 1.40Å

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