1ri2

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ri2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Encephalitozoon_cuniculi Encephalitozoon cuniculi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RI2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RI2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ri2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Encephalitozoon_cuniculi Encephalitozoon cuniculi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RI2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RI2 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTG:7-METHYL-GUANOSINE-5-TRIPHOSPHATE-5-GUANOSINE'>GTG</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTG:7-METHYL-GUANOSINE-5-TRIPHOSPHATE-5-GUANOSINE'>GTG</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ri1|1ri1]], [[1ri3|1ri3]], [[1ri4|1ri4]], [[1ri5|1ri5]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ri1|1ri1]], [[1ri3|1ri3]], [[1ri4|1ri4]], [[1ri5|1ri5]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ECU10_0380 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6035 Encephalitozoon cuniculi])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ECU10_0380 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6035 Encephalitozoon cuniculi])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ri2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ri2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ri2 RCSB], [http://www.ebi.ac.uk/pdbsum/1ri2 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ri2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ri2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ri2 RCSB], [http://www.ebi.ac.uk/pdbsum/1ri2 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MCES_ENCCU MCES_ENCCU]] mRNA-capping methyltransferase that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC.<ref>PMID:15760890</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Encephalitozoon cuniculi]]
[[Category: Encephalitozoon cuniculi]]
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[[Category: Fabrega, C.]]
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[[Category: Fabrega, C]]
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[[Category: Hausmann, S.]]
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[[Category: Hausmann, S]]
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[[Category: Lima, C D.]]
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[[Category: Lima, C D]]
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[[Category: Shen, V.]]
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[[Category: Shen, V]]
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[[Category: Shuman, S.]]
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[[Category: Shuman, S]]
[[Category: Cap]]
[[Category: Cap]]
[[Category: M7g]]
[[Category: M7g]]

Revision as of 17:59, 25 December 2014

Structure and mechanism of mRNA cap (guanine N-7) methyltransferase

1ri2, resolution 2.70Å

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OCA

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